The Methodist Hospital

The Methodist Hospital System

Tatiana Wolfe

Philip J Horner

Matthew K Hogan

Gavin W Britz

Eugene V Golanov

Philip John Horner

Caio C Quini

The exemplified system and method facilitate an objective, non-invasive measurement of myelin quality and integrity in living brains based on isolation of myelin-specific magnetic relaxation constants in k-space. The system uses magnetic resonance (MR) signals to select signatures specific to, or associated with, myelin and its structure and to then encode the selected signatures into an image or model to which the quantitative myelin health information can be co-registered with 2D, 3D visualization, and tractography of the myelin-signal isolated MR information. The system also sets a model for digital hierarchical learning of biomedical signals in MR, and beyond, based on experimental data in which it executes the herein described signal isolation operations.

Signal isolation magnetic resonance image (SIMRI) and methods thereof

Example neurostimulation induced medicine devices and methods of use are described herein. An example endotracheal device can include an elongate tubular member having a proximal end and a distal end, an inflatable cuff arranged between the proximal and distal ends of the elongate tubular member, and an electrode array disposed in proximity to an exterior surface of the inflatable cuff. The inflatable cuff can be configured to expand to contact a subject's tracheal wall. Additionally, the electrode array can include a plurality of flexible electrodes, where a set of the flexible electrodes anatomically align with a region of the subject's tracheal wall for selectively targeting vagus nerve activity.

Neurostimulation induced medicine devices and related methods of use

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Hilliard, OH, United States of America

Tatiana Wolfe