Shionogi Company Limited

Tasuku Tsukamoto

Tatsuya Takahashi

Yoshito Numata

Shoichi Naito

Junji Onoda

Shoji Yamane

Katsutoshi Yamada

Kazuhiko Maekawa

Yasuhiko Sato

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Method of inhibiting the enzymatic activity of vascular endothelial lipase with a monoclonal antibody

Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Monoclonal antibody against EL which inhibits enzyme activity of EL

Growing community of inventors

Toyonaka, Japan

Tasuku Tsukamoto