Nikon Corporation

The University of Tokyo

Sustainable Medicine, Inc.

Susmed, Inc.

Taro Ueno

Ryo Kobayashi

Naoya Ishizawa

Takanori Ichiki

Hirofumi Shiono

Kenji Miyamoto

Masashi Kobayashi

Takashi Funatsu

Shoichi Tsuchiya

Masaaki Tanabe

Tetsuomi Takasaki

Takanori Akagi

Keiji Mitsui

Ayako Hayashi

Flow channel plate of a cartridge for medical testing equipment

A bedtime setting unitsetting a target bedtime, on the basis of a sleep efficiency of a user, and a compliance status index value calculation unitcalculating a compliance status index value representing a compliance status with the set target bedtime are provided, and in a case where the sleep efficiency is less than a first predetermined value and the compliance status index value is a threshold value or more, a time later than the previous set bedtime is set as the next bedtime, in a case where the sleep efficiency is less than the first predetermined value and the compliance status index value is less than the threshold value, a time identical to the previous set bedtime is set as the next bedtime such that even in a state where it is necessary to set the bedtime to be later than the previous set bedtime since the sleep efficiency is less than the first predetermined value, a time identical to the previous set bedtime is set as the next bedtime in a case where the compliance status index value is less than the threshold value, and thus, a bedtime that applies a large burden on a user without an excellent compliance status with the bedtime is not set.

Insomnia treatment assistance device, insomnia treatment assistance system, and insomnia treatment assistance program

A method of manufacturing a fluidic device includes molding either one of the base member and the valve part with a first mold; and molding the other one of the base member and the valve part with a second mold with respect to the molded base member or the molded valve part.

Fluidic device, method of manufacturing fluidic device, and valve for fluidic device

A solution mixer comprising: a main flow path in which a solution circulates; at least one solution introduction flow path connected to the main flow path; and at least one solution discharge flow path connected to the main flow path, wherein the solution discharge flow path has at least one solution discharge flow path valve, and wherein the main flow path has at least one main flow path valve.

Solution mixer, fluidic device, and solution mixing method

A fluid device includes a substrate and a gas-liquid separating filter, the substrate has a flow path through which a solution flows, a reservoir, in which the solution is accommodated, connected to the flow path, an injection hole configured to connect the reservoir to the outside, and an air introduction hole branched off from the injection hole and connected to the outside, and the gas-liquid separating filter is disposed in a path of the air introduction hole, allows passage of a gas flowing through the air introduction hole, and prevents passage of a liquid flowing through the air introduction hole.

Fluid device and fluid control system

The present invention aims at providing a fluidic device that can hold a large amount of solutions in a reservoir without depending on an attitude. The reservoir includes a meandering flow path including: a plurality of first flow paths that extend linearly along a first direction and that are arranged to be spaced in a second direction crossing the first direction; and a second flow path that extends linearly along the second direction such that a connection between first end sides of the adjacent first flow paths and a connection between second end sides of the adjacent first flow paths are alternately switched along the second direction for each first flow path, wherein the meandering flow path meanders along the second direction. When the length of each of the first flow path and the second flow path is L, a surface tension is &#x3b3;, the density of the solution is &#x3c1;, the acceleration which includes a gravity and which is applied to the solution is G, the wetted perimeter length of the first flow path and the second flow path is Wp, a cross-sectional area of the first flow path and the second flow path is A, a receding contact angle is &#x3b1;, and an advancing contact angle is &#x3b2;, a relationship L&#x2264;(&#x3b3;&#xd7;Wp&#xd7;(cos &#x3b1;&#x2212;cos &#x3b2;))/(&#x3c1;&#xd7;A&#xd7;G) is satisfied.

Fluidic device

A fluidic device includes a first circulation flow path and a second circulation flow path which circulate a solution containing a sample material, the first circulation flow path and the second circulation flow path share at least a part of the flow path, and at least one selected from the group consisting of a capture unit which captures the sample material, a detection unit which detects the sample material, a valve, and a pump is provided on the shared flow path.

Fluidic device, system, method of detecting sample material and method of purifying sample material

A fluidic device includes: a circulation flow path; and a capture part arranged on the circulation flow path and configured to capture a sample substance in a solution and/or a detection part arranged on the circulation flow path and configured to detect a sample substance in a solution. A method of capturing a sample substance that is bound to a carrier particle, using a fluidic device which includes a circulation flow path and a capture part arranged on the circulation flow path and configured to capture the carrier particle and in which the circulation flow path has two or more circulation flow path valves, includes: an introduction step of, in a state where the circulation flow path valve is closed, introducing a solution that includes a sample substance to at least one of partitions partitioned by the circulation flow path valve and introducing a solution that includes a carrier particle which is bound to the sample substance to at least another of the partitions; a mix step of opening all of the circulation flow path valves and circulating and mixing a solution in the circulation flow path; and a capture step of capturing the carrier particle by the capture part.

Fluidic device, system, and method

Provided is an insomnia treatment assistance device including: a bedtime setting unit that sets a bedtime of a user on the basis of sleep efficiency of the user and notifies it to the user; an execution time setting unit that sets a time earlier than the bedtime by a first predetermined time as a sleepiness test execution time; and a reminder message presentation unit that presents a reminder message for prompting execution of a sleepiness test to the user at the sleepiness test execution time. The sleepiness test can be performed at an appropriate time depending on the sleep efficiency that suggests a degree of amelioration of insomnia even in a case where the sleepiness test is performed once a day. It is possible to appropriately measure user's sleepiness depending on the degree of amelioration of insomnia while minimizing a user's burden for the sleepiness test.

Insomnia treatment assistance device and insomnia treatment assistance program

Computer screen with graphical user interface

The present invention provides a fluidic device, an exosome analysis method, a biomolecule analysis method, and a biomolecule detection method, which can analyze even the content of an exosome in a series of flows by introducing a sample into the device. A fluidic device of the present invention is a fluidic device which detects a biomolecule contained in an exosome in a sample, and includes: an exosome purification unit which has a layer modified with a compound having a hydrophobic chain and a hydrophilic chain; a biomolecule purification unit; a biomolecule detection unit; a first flow path which connects the exosome purification unit to the biomolecule purification unit; and a second flow path which connects the biomolecule purification unit to the biomolecule detection unit.

Fluidic device, exosome analysis method, biomolecule analysis method, and biomolecule detection method

A method for detecting a target nucleic acid, comprising: (a) contacting a nucleic acid sample comprising a target nucleic acid, comprising a first portion and a second portion, with: (i) a detection probe, wherein the detection probe is labeled with a labeling substance and comprises a nucleic acid sequence that forms a stem-loop structure and having a 5' protruding end or a 3&#x2032; protruding end that is capable of hybridizing to the second portion, and (ii) a capture probe comprising a nucleic acid sequence capable of hybridizing to the first portion, wherein the capture probe is immobilized to a substrate, under conditions to form a target nucleic acid-detection probe-capture probe complex by hybridizing the second portion to the detection probe and hybridizing the first portion to the capture probe; (b) ligating a first end of the detection probe with an end of the target nucleic acid and ligating a second end of the detection probe with an end of the capture probe; and (c) detecting the labeling substance of the nucleic acid-detection probe-capture probe complex formed on the substrate.

Growing community of inventors

Tokyo, Japan

Taro Ueno