The Brigham and Women's Hospital, Inc.

Tarawatie E Deelman

Jeffrey Michael Karp

Yuhan Lee

Ali Tavakkoli

This disclosure relates to compositions including formulated sucralfate or other aluminum-crosslinked sulfated agents for delivery of agents to biological surfaces and/or the modulation of nutrient absorption through the intestinal lining as well as methods for the manufacture of and the use of these compositions for treating disorders including diabetes type II and clinical obesity that require a modulation of certain nutrients to the body.

Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients

This disclosure relates to compositions including formulated sucralfate or other aluminum-crosslinked sulfated agents for the modulation of nutrient absorption through the intestinal lining as well as methods for the manufacture of and the use of these compounds for treating disorders requiring a modulation of certain nutrients to the body including diabetes type II and clinical obesity.

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Boston, MA, United States of America

Tarawatie E Deelman