Commonwealth Scientific and Industrial Research Organisation

Other

Tara Sutherland

Victoria Shirley Haritos

Sarah Weisman

Alagacone Sriskantha

Robyn Joyce Russell

John Graham Oakeshott

Peter Malcolm Campbell

Irene Horne

Rebecca Harcourt

Holly Trueman

John Alan Maurice Ramshaw

Shoko Okada

Yong Yi Peng

Andrew Allan Walker

Michael George Huson

Trevor Rapson

Jeffrey Scott Church

The present invention relates to compositions comprising: a polypeptide, wherein at least a portion of the polypeptide has a coiled coil structure; and a chelate comprising a chelating agent and a metal ion; and wherein the chelate is bound to at least one amino acid of the polypeptide. In a preferred embodiment the polypeptide is a silk fibroin, wherein at least a portion of the silk fibroin has a coiled coil structure.

Metalloprotein compositions

The present invention provides silk proteins, as well as nucleic acids encoding these proteins. The present invention also provides recombinant cells and/or organisms which synthesize silk proteins. Silk proteins of the invention can be used for a variety of purposes such as in the manufacture of personal care products, plastics, textiles, and biomedical products.

Silk proteins

The present invention relates to silk proteins which can be used to produce silk with a collagen-like structure, as well as nucleic acids encoding such proteins. The present invention also relates to recombinant cells and/or organisms which synthesize silk proteins. Silk proteins of the invention can be used for a variety of purposes such as in the production of personal care products, plastics, textiles, and biomedical products.

Collagen-like silk genes

The present invention relates to methods of producing silk dope comprising silk proteins with a coiled-coil structure such as honeybee silk proteins. The silk proteins are obtained from cells producing them, solubilizing the proteins by contacting them with a surfactant or an ionic liquid and concentrating the proteins to produce silk dope. The proteins can be used for a variety of purposes such as in the production of personal care products, plastics, textiles and biomedical products.

Processes for producing silk dope

The present invention provides enzymes capable of hydrolysing organophosphate (OP) molecules. In particular, the invention provides a phosphotriesterase enzyme identified from anstrain isolated from soil that hydrolyses OP pesticides, and the gene encoding that enzyme. The invention also provides mutants of the identified phosphotriesterase enzyme which have altered substrate specificity. The use of these enzymes in bioremediation strategies is also provided.

Phosphotriesterase from agrobacterium radiobacter P230

Phosphotriesterase from agrobacterium radiobacter p230

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Watson, Australia

Tara Sutherland