Shanghai Huahong Grace Semiconductor Manufacturing Corporation

Other

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Medshine Discovery Inc.

East China Normal University

Fujian Akeylink Biotechnology Co., Ltd.

Cisen Pharmaceutical Co., Ltd.

Cgenetech (suzhou, China) Co., Ltd.

D3 Bio (wuxi) Co., Ltd.

Huaqin Technology Co., Ltd.

Qingdao Huanghai Pharmaceutical Co., Ltd.

Shenzhen Salubris Pharm Co Ltd.

Chinese Academy of Sciences

Tongji University

Fujian Cosunter Pharmaceutical Co., Ltd.

Tao Yu

Chengde Wu

Shuhui Chen

Ning Li

Qinghua Mao

Yi Li

Jiahu Wu

Lu Gan

Bo Gao

Jian Li

Yong Wang

Yi Bu Li

Hong Tao Liu

Zheng Wang

Jie Shen

Feng Guo

Ming Yang

Jie Gandalf Yan

Huiping Amy Guan

Jikui Sun

Hongwei Liu

Changjun Wang

Binghan Li

Zhiliu Zhang

Jie Ren

Zongbin Li

Ning Liu

Qi Huang

Chao Peng

Xiang Fan

Lingwei Kong

Nengyang Shi

Wenjie Xu

Dongling Hao

Rongchang Zhu

Yunjie Tang

Xiao Xia

Shengbin Zhang

Yusheng Fu

Yong Tian

Hongxing Hu

Zhenxia Wang

Wendong Cheng

Huibin Huang

Peng Zeng

Heng Hu

Ronggui Hu

Shenggang Cui

Bokchul Shin

Yuncai Tian

Jinhai Chen

Peipei Jiang

Zhemin Rong

Xinyu Zhou

Yonghui Tao

Xiao Yu

Huiping Guan

Compounds as SGLT2/DPP4 dual inhibitors, and application in preparation of medicines as the SGLT2/DPP4 dual inhibitors. A compound represented by formula (I), and an isomer or pharmaceutically acceptable salt thereof are specifically involved.

SGLT2/DPP4 inhibitor and application thereof

A Spiro compound serving as an ERK inhibitor, and an application thereof in preparing a drug for treating an ERK-related disease. The present invention specifically relates to a compound represented by formula (III) or a pharmaceutically acceptable salt thereof.

Spiro compound serving as ERK inhibitor, and application thereof

A class of compounds as a SGLT1/SGLT2/DPP4 triple inhibitor, and an application in preparation of a drug serving as the SGLT1/SGLT2/DPP4 triple inhibitor. Compounds represented by formula (I), and isomers and pharmaceutically-acceptable salts thereof are specifically involved.

SGLTS/DPP4 inhibitor and application thereof

Provided are a preparation method for a powder product, a powder product, and a powder commodity. The preparation method for a powder product includes the following steps: mixing 30% to 50% by mass of an oil-phase component and 50% to 70% by mass of a water-phase component to form a powder mixture liquid, feeding the powder mixture liquid into a mold, and baking the powder mixture liquid until its moisture content is ≤20%, to obtain a powder base product; cooling the powder base product to a predetermined temperature to obtain a solidified powder base product; releasing the solidified powder base product from the mold, and vacuum freeze-drying under a vacuum negative pressure condition. The powder product obtained by the freeze-drying is less prone to cakey makeup or powder floating, has a lighter and thinner skin feeling, and is fitter to skin.

Preparation method for powder product, powder product, and powder commodity

A glucoside derivative that acts as an SGLT1 inhibitor and an application thereof in the preparation of a drug for SGLT1 related diseases. Specifically disclosed is a compound represented by formula (II), a tautomer thereof or a pharmaceutically acceptable composition thereof.

Glucoside derivative that acts as SGLT1 inhibitor and application thereof

The present disclosure provides a method for detecting controller area network (CAN) bus intrusion of a vehicle-mounted network based on a Gaussian mixture model-hidden Markov model (GMM-HMM), including the following steps: obtaining a normal packet of a CAN bus of a vehicle-mounted network, and counting cycles of all packets of each CAN ID based on a time sequence, that is, a time difference between two frames of packets of a same CAN ID, to form a cycle sequence as an input of an algorithm; dividing the cycle sequence of each CAN ID into a fixed length based on the algorithm, and then training a GMM-HMM for each CAN ID to obtain a likelihood probability of a normal cycle sequence; and further counting a cycle sequence of each CAN ID for a tested packet sequence, calculating, after the cycle sequence is input a model, a likelihood probability of generating the sequence, and determining whether the packet sequence is abnormal by comparing the likelihood probability with a threshold of the likelihood probability obtained in the previous step. In the present disclosure, anomaly detection of a packet cycle of a CAN bus is implemented, such that attack behaviors of inserting packets into the bus such as DoS, blur, and replay can be detected.

Method for detecting CAN bus intrusion of vehicle-mounted network based on GMM-HMM and system

Provided are crystal forms A, B, C and D of a compound of formula (I), and application of the crystal forms in the preparation of drugs for treating ASK1-related diseases.

Crystal form as ASK1 inhibitor and preparation method and application thereof

A substrate in a split-gate memory device has a memory cell region including a connecting subregion and a functional subregion. A source region is formed in the substrate, and first and second gate structures mirrored to each other are formed on the substrate on opposing sides of the source region. In the connecting subregion, control gates of the first and second gate structures and the source region are electrically connected by electrical connections. In the split-gate memory device, the arrangement of the functional and connecting subregions in the memory cell region and external connection of the control gates in the first and second gate structures and the source region in the connecting subregion, which are exposed by etching, by the electrical connections in the connecting subregion result in area savings of the memory cell region.

Split-gate memory device and method of forming same

The present disclosure provides a memory and a method for forming the memory. The memory includes: a substrate including a first storage area and a second storage area; a source region disposed in the substrate between the first storage area and the second storage area; a first drain region and a second drain region in the substrate on both sides of the first storage area and the second storage area; a first storage structure disposed on the first storage area, including a first storage unit, a second storage unit, and a first word line gate; and a second storage structure disposed on the second storage area, including a third storage unit, a fourth storage unit, and a second word line gate. The memory can obtain an improved performance.

Memory and method for forming the same

A novel five-membered heteroaromatic imidazole compound and use thereof is disclosed herein. Specifically, disclosed is a compound as shown in formula (III) or a pharmaceutically acceptable salt thereof. Also disclosed is a method for treating a disease related to GLP-1 receptor such as type II diabetes. 

Five-membered heteroaryl-fused imidazole compound and application thereof

An interface display method and an electronic device are provided. The interface display method comprises steps of: during processing an interface display request of an application program, determining whether the interface display request meets a preset condition or not (); if the interface display request meets the preset condition, acquiring at least one fingerprint acquisition area according to the interface display request (); displaying an interface according to the interface display request (), and activating a fingerprint recognition sensor corresponding to the at least one fingerprint acquisition area (); and if the interface display request does not meet the preset condition, displaying the interface according to the interface display request, and controlling the fingerprint recognition sensor of the electronic device to be in an inactive state (). The method reduces the power consumption of the electronic device, and prolongs the service life of the electronic device.

Interface display method to reduce power consumption of electronic device with fingerprint sensor

The present disclosure provides a memory and a method for forming the memory. The method includes: providing a base with a first fin and a second fin formed thereon, wherein the first fin comprises an erasing region and a floating gate region on both sides of the erasing region, and a sacrificial layer is disposed on a surface of the erasing region and a surface of the second fin; forming a floating gate structure across the floating gate region on the base; forming a first sidewall film on a top surface and sidewall surfaces of the floating gate structure on the base; removing the sacrificial layer, and forming an opening in the floating gate structure and the first sidewall film; and forming an erasing gate structure in the opening. The memory formed by the method has good performance.

Disclosed in the present invention are a compound as shown in formula (II), a tautomer or a pharmaceutically acceptable salt thereof, and also disclosed is the use thereof in preparing a drug for treating an ASK1-associated disease. 

Pyridine derivative as ASK1 inhibitor and preparation method and use thereof

A compound as an SGLT1/SGLT2 dual inhibitor, and an application thereof in the preparation of a drug as the SGLT1/SGLT2 dual inhibitor. The compound is a compound represented by formula (I), an isomer thereof, or a pharmaceutically acceptable salt thereof. 

SGLTS inhibitor and application thereof

The present disclosure relates to a compound as shown in formula (II), a tautomer or a pharmaceutically acceptable salt thereof, and disclosed is the use thereof in preparing a drug for treating an ASK1-associated disease. 

ASK1 inhibitor and preparation method and use thereof

Growing community of inventors

Shanghai, China

Tao Yu