Alexion Pharmaceuticals, Inc.

Taneisha Ann-Tanara Mack

Douglas L Sheridan

Paul P Tamburini

Walter C Voegtli

Tadas Panavas

Provided herein are antibodies, or antigen binding portions thereof, that bind to CD200. Also provided are uses of these proteins in therapeutic applications, such as the treatment of cancer and in conjunction with organ transplantation. Also provided are nucleic acids encoding the heavy and/or light chain variable regions (or heavy and/or light chains) of the antibodies, vectors comprising the nucleic acids, and cells that produce the antibodies.

Humanized anti-CD200 antibodies and uses thereof

Described herein are isolated monovalent antibodies or antibody fragments thereof that bind human properdin. Such antibodies are useful in methods of treatment for diseases mediated by alternative complement pathway dysregulation.

Growing community of inventors

East Hampton, CT, United States of America

Taneisha Ann-Tanara Mack