Eveliqure Biotechnologies Gmbh

Tamás Henics

Eszter Nagy

Gábor Nagy

Valeria Szijárto

A live attenuatedvaccine, which is based on a roughstrain lacking LPS O-antigen which is non-invasive through a mutation of the invasion plasmid, specifically for use in the immunoprophylaxis of a subject to prevent infectious diseases, preferably enteral disease, and astrain, which is a2a strain with a deletion of the rfb F, ipa B and/or ipa C genes, as well as a recombinant plasmid vector based on a mutatedinvasion plasmid comprising a nucleotide sequence encoding at least one heterologous antigen, wherein the plasmid is mutated in at least one of the ipa B and/or ipa C genes.

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Vienna, Austria

Tamás Henics