Nektar Therapeutics

Tamra L Barker

Michael A Eldon

Shibani S Harite

Provided herein are compounds and methods for achieving a sustained therapeutic effect of small molecule anti-cancer agents when administered in vivo. Sustained Exposure to Active Metabolite with PEG-Irinotecan

Compositions and methods for achieving sustained therapeutic drug concentrations in a subject

Among other things, a method of treating a human having brain cancer is, the method comprising administering via a non-continuous dosing regimen to the human having brain cancer, a therapeutically effective amount of a pharmaceutical composition comprising a prodrug or a pharmaceutically acceptable salt thereof, wherein the non-continuous dosing regimen comprises administering the pharmaceutical composition no more frequently than once every seven days for at least two dosings.

Methods for treating humans having brain cancer

Provided herein are compounds and methods for achieving a sustained therapeutic effect of small molecule anti-cancer agents when administered in vivo.

Growing community of inventors

Davis, CA, United States of America

Tamra L Barker