Daikyo Gomu Seiko, Ltd.

Yamanouchi Pharmaceutical Company Ltd.

Daikyo Gomu Sekio Ltd.

Tamotsu Okuda

Denpei Sudo

Hideo Yoshitaka

Yutaka Tatsumi

Tatsuya Matsunaga

Masamichi Sudo

Tomoyasu Muraki

A process for molding a resin-laminated rubber closure for a medical vial. This closure includes an annular leg part to be inserted into the mouth of the vial, which leg part is notched or cut at least at one position and a flange part to be contacted with the front surface of the vial mouth. The outer and inner surfaces of the annular leg part are laminated with a chemical-resistant resin film except for the upper end of the leg part so that the rubber surface is exposed at the upper end of said leg portion. The leg part has at least one protrusion on the outer surface of the laminated portion.

Process for the production of a resin-laminated rubber closure for a

A sliding stopper for a syringe, consisting of a rubber elastic body having the part to be contacted with a liquid medicament and the part sliding on the inner wall of a barrel fully laminated with a film of tetrafluoroethylene resin, ethylenetetrafluoroethylene resin or ultra-high molecular weight polyethylene resin, and having an excellent liquid tightness and gas tightness. The ratio of the length (Y) of the surface of the outer circumferential part of the sliding stopper contacting the inner wall of the barrel to the length (L) of the sliding part of the sliding stopper, i.e. Y/L is in the range of 0.80 to 1.00, and the ratio of the length (L) of the sliding part to the outer diameter (D) of the sliding stopper, i.e. L/D is in the range of 0.25 to 1.00.

Sliding stopper for a syringe

A laminated sliding stopper for a syringe, excellent in sliding or moving property and free from contamination of an injection liquid, is provided which consists of a rubber elastic body whose part to be contacted with the injection liquid and sliding part on the inner wall of the barrel are fully laminated with a film of tetrafluoroethylene.

Laminated sliding stopper for a syringe

A resin-laminated rubber closure for a medical vial is provided herein. This closure comprises an annular leg part to be inserted into the mouth of the vial, which leg part is notched or cut at least at one position and a flange part to be contacted with the front surface of the vial mouth, wherein the outer and inner surfaces of the annular leg part is provided with a chemical-resistant resin film laminated thereon except for the upper end of the leg part so that the rubber surface is exposed at the upper end of said leg portion, and wherein the leg part has at least one protrusion on the outer surface of the laminated portion. The present invention also relates to a molding process for economically producing said closure.

Growing community of inventors

Noda, Japan

Tamotsu Okuda