Bristol-Myers Squibb Compnay

Other

Fujifilm Corporation

Tamotsu Furumai

Masatoshi Kakushima

Masami Hatori

Yasuhiro Igarashi

Seikichi Kobaru

Chiharu Ikeda

Yukio Sato

Toshikazu Oki

Kyoichiro Saitoh

Tomio Nishimura

Hitoshi Kunoh

Masafumi Shimizu

Yoichiro Saitoh

A dicarboxylic acid compound obtainable by oxidative degradation of pradimicin antibiotics, which are antibiotics consisting of the benzonaphthacene skeleton, a D-amino acid side chain and a sugar chain, for the second saccharide residue of the sugar chain, and use thereof utilizing a specific microorganism binding property thereof are provided. The dicarboxylic acid compound has significantly improved water-solubility compared with the raw material antibiotics, whist maintaining the specific microorganism binding property.

Benzonaphthacene glycoside derivative and use thereof

A disease control agent and a phytoalexin inducing agent, comprising Streptomyces sp. R-5 as an active ingredient are disclosed. Disease-resistant plants may be produced by inoculating plants with the disclosed Streptomyces sp. R-5. The disease control agent and a phytoalexin inducing agent are further useful in that they have low toxicity to humans and cause no environmental contamination.

Plant disease control agent

The present invention relates to a fermentation process for producing BMY-28960 and desxylosyl BMY-28960, and to a novel BMY-28960-producing organism belonging to the genus Actinomadura and designated as strain AB 1236 (ATCC 55208).

Production of pradimicin antibiotics

Growing community of inventors

Yokohama, Japan

Tamotsu Furumai