The Procter Gamble Company

Warner Chilcott Company, LLC

Tammy K Baker

Arif Ali Baig

Samuel James St John

William Michael Glandorf

Aaron Reed Biesbrock

Nicholas William Geary

Nancy Lee Redman-Furey

Oral care compositions with an anticaries or anticavity effect. Oral care compositions that have an extract from a species in thefamily and an anticaries drug, such as a fluoride ion source. Oral care compositions have fluoride and hops beta acid, such as from an extract from. Oral care compositions have a fluoride ion source and a hops beta acid derived from an extract of

Oral care compositions comprising hops beta acids and fluoride ions

A dentifrice composition including from about 0.0025% to about 5%, by weight of the dentifrice composition, of a tin ion source, where the tin ion source does not comprise stannous fluoride, calcium carbonate, and up to about 45%, by weight of the dentifrice composition, of water. The dentifrice composition has a pH of greater than 7.

Dentifrice compositions comprising tin ions

A dentifrice composition includes tin, from about 5% to about 50%, by weight of the dentifrice composition, of polyol, and up to about 45%, by weight of the composition, of water. The polyol includes xylitol, sorbitol, or combinations thereof. The dentifrice composition has a pH of greater than 7.

Oral care compositions comprising tin ions

A dentifrice composition with tin, calcium, and a pH of greater than 7. A dentifrice composition with tin, fluoride, calcium abrasive, water, and a pH of greater than 7. Dentifrice compositions with a high tin ion availability. Dentifrice compositions comprising stannous fluoride and/or stannous chloride in combination with calcium carbonate.

An oral care composition with tin, polyol with five or more carbon atoms, water, and a pH of greater than 7. An oral care composition with a tin ion source, a fluoride ion source, a polyol with five or more carbon atoms, water, and a pH of greater than 7. Oral care compositions with a high tin ion availability.

Oral care compositions with an anticaries or anticavity effect. Oral care compositions that are have an extract from a species in the Humulus family and an anticaries drug, such as a fluoride ion source. Oral care compositions have fluoride and hops beta acid, such as from an extract from. Oral care compositions have a fluoride ion source and a hops beta acid derived from an extract of

The present invention is directed to solvates and various polymorphic forms of (E)-1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride and pharmaceutical compositions thereof.

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South Lebanon, OH, United States of America

Tammy K Baker