Rutgers, The State University of New Jersey

Other

Tamara Minko

Olga B Garbuzenko

Joseph R Bertino

Patrick J Sinko

Stanley Stein

Debabrata Banerjee

John E Kerrigan

Xiaoqi Xie

Emine E Abali

Kathleen W Scotto

Xiaoping Zhang

Gregory Charles Williams

Bo Qiu

Michael Leibowitz

Vera Ivanova

Srinivasan Ramanathan

Goubao Zhang

Shahrair Pooyan

Seong Hee Park

Pankaj Paranjpe

Lorna Rodriguez-Rodriguez

Oleh Taratula

Vatsal Shah

A nanocarrier containing a combination of bioactive agents is provided. The nanocarrier allows for targeted delivery of the agents to cancer cells with minimized side effect.

Strategies to enhance lung cancer treatment

This invention relates to lipid nanoparticle compositions and methods for the localized delivery of active agents via inhalation therapy.

Nanotechnology approach for inhalation therapies

The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.

E2F as a target of hormone refractory prostate cancer

The present invention provides compositions and methods for the delivery of nucleic acids to a cell. The present invention additionally provides compositions and methods for the treatment of a disease or disorder, particularly cancer. In a particular embodiment, the composition comprises at least one pharmaceutically acceptable carrier and at least one liposome or dendrimer comprising at least two chemotherapeutic agents with different mechanisms of action and at least two inhibitors of cellular drug resistance.

Compositions and methods for delivering nucleic acid molecules and treating cancer

The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses.

Complex drug delivery composition and method for treating cancer

The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents

Growing community of inventors

Somerset, NJ, United States of America

Tamara Minko