Exact Sciences Corporation

Third Wave Technologies, Inc.

Mayo Foundation for Medical Education and Research

Exact Sciences Development Company, LLC

Tamara J Sander

Hatim T Allawi

Graham P Lidgard

Michael W Kaiser

Marilyn C Olson-Munoz

Hon Ip

Vecheslav A Elagin

Poonam Agarwal

William Russell Taylor

Robert W Kwiatkowski, Jr

Abram Michael Vaccaro

Sarah Olson

Michelle Curtis

Robert W Kwiatkowski

Angela Hudson

Michelle Garsha

Ilse Tyler

Brian Aizenstein

Maria Giakoumopoulos

Melissa M Gray

Chateen Krueger

Slava Elagin

Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.

Detection of lung neoplasia by amplification of RNA sequences

Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.

Detection of colon neoplasia by analysis of methylated DNA

Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.

Isolation and detection of DNA from plasma

The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.

Detection of HPV

Growing community of inventors

Mazomanie, WI, United States of America

Tamara J Sander