Omrix Biopharmaceuticals Inc.

Ethicon, Gmbh

Tamara Byk-Tennenbaum

Sivan Doron

Lior Weissman

Erez Ilan

Israel Nur

Yair Pilpel

Yuri Zherdev

Eve Montia

James Galloway

Itai Podoler

Jared Schneider

John Mott Goodman

John Anastasiadis

Kenneth M Tamsula

The invention relates to a viral inactivated biological liquid or dry mixture and to its preparation. Principally, the invention relates, but is not limited, to a mixture derived from a platelet source.

Viral inactivated biological mixture

The present invention is directed to methods of enhancing toxicity of a glycolytic dependent compound towards a cancerous tissue and/or organ in a subject, the method being comprised of targeting the glycolytic dependent compound to the cancerous tissue and/or organ by placing oxidized regenerated cellulose (ORC) and/or oxidized cellulose (OC) in direct connection with the cancerous tissue and/or organ, and administering the glycolytic dependent compound to the subject by a systemic route.

Method of treating a disease using a glycolytic dependent compound

The present invention is directed to compounds, methods for stabilizing thrombin activity with a thrombin binding oligonucleotide and to stabilized thrombin. The thrombin binding oligonucleotide is capable of inhibiting thrombin activity whereby the inhibition can be reversed with an antisense oligonucleotide.

Stabilized thrombin

Provided is a method of enhancing toxicity of a glycolytic dependent compound towards a cell, tissue and/or organ e.g. a diseased cell, tissue and/or organ, the method comprises contacting Oxidized Regenerated Cellulose (ORC) and/or Oxidized Cellulose (OC); and a glycolytic dependent compound with the cell, tissue and/or organ. The ORC and/or OC; and the glycolytic dependent compound are contacted with the cell, tissue and/or organ in a non-blended form.

Apparatuses and methods for delivery of fluid materials, particularly multi-part fluid materials, including modular apparatuses in which various components are maintained separately until ready for use. Each fluid component is maintained in a separate housing until mixing of the fluid components is desired. Maintaining components separately until use allows for proper filling, sterilization, packaging and storing until use.

Modular apparatus for delivery of fluid materials

Kit with stabilized thrombin

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Kiryat Ono, Israel

Tamara Byk-Tennenbaum