Bar-ilan University

Medical Research Fund of Tel Aviv Sourasky Medical Center

Healor Ltd.

Arava Bio-tech Ltd.

Heal0r, Ltd.

Tamar Tennenbaum

Liora Braiman-Wiksman

Varda Deutsch

Ron Goldstein

Addy Alt

Toshio Kuroki

Sanford Sampson

Shlomo Margel

Liat Hammer

Shlomzlon Shen

Larisa Sheihet

Shlomzion Shen

Moshe Ben-Hamo

Ephraim Brener

Marina Gartsbein

Yuvai Sagiv

Michal Meir

Inessa Solominik

Revital Mandil-Levin

The present disclosure relates to compositions and methods for treating acne and other conditions. In particular, the compositions and methods are useful for the treatment of sebum associated conditions.

Visfatin therapeutic agents for the treatment of acne and other conditions

The present invention relates to animal model systems comprising a chimera between an avian embryo and a mammalian organism. Specifically, chimeric model systems comprising normal, diseased or genetically transformed mammalian cells and tissues transplanted into avian embryos, and uses thereof for in vivo testing of drugs and therapeutic modalities are disclosed.

Chimeric avian-based screening system containing mammalian grafts

Method and compositions are provided for treating or preventing a skin pathology or disorder associated with diabetes and/or aging, by topical administration of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology or disorder. Examples of such agents include PKC modulating agents, various adipokines and insulin signaling related molecules. In particular, restoration of the subcutaneous adipose tissue can overcome many of the diabetic skin pathologies and aging skin disorders and conditions.

Method and compositions for prevention and treatment of diabetic and aged skin

The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. Exemplary modulators include inhibitors of PKC-alpha, PKC-epsilon and PKC-eta, as well as activators of PKC-delta.

Method for treatment of inflammatory disease and disorder

A pharmaceutical composition and method for inducing or accelerating a healing process of a skin wound are described. The pharmaceutical composition contains, as an active ingredient, a therapeutically effective amount of at least one agent for modulating PKC production and/or activation, and a pharmaceutically acceptable carrier. The method is effected by administering the composition to a wound.

Methods and pharmaceutical compositions for healing wounds

Thrombin-conjugated nanoparticles, wherein said nanoparticles comprise one or more organic and/or inorganic compounds and process for preparing the same are provided. The thrombin-conjugated nanoparticles are suitable for use in the preparation of fibrin-based biological sealant.

Biological glue based on thrombin-conjugated nanoparticles

A pharmaceutical composition and method for inducing or accelerating a healing process of a skin wound are described. The pharmaceutical composition contains, as an active ingredient, a therapeutically effective amount of an agent for either enhancing PKC production and/or enhancing PKC activation; and a pharmaceutically acceptable carrier. The method is effected by administering the composition to a wound.

Growing community of inventors

Jerusalem, Israel

Tamar Tennenbaum