Omrix Biopharmaceuticals Inc.

Ethicon, Gmbh

Tamar Auerbach-Nevo

Israel Nur

Nadav Orr

Ashley DeAnglis

Tali Negreanu-Gilboa

Erez Ilan

Dwayne Lee Looney

Yi-Lan Wang

Roberto Meidler

Omri Faingold

Oleg Belyaev

Elena Grimberg

Yonit Tiberman

Hadas Alperin

An expandable biodegradable hemostatic matrix comprised of oxidized cellulose, and having a density ranging from about 0.8 to about 1.2 gr/cmis disclosed herein. The matrix may be expandable to at least 3 times its original volume within 4 sec upon contact with an aqueous solution room temperature. Further disclosed are methods for making the hemostatic matrix as well as method of treating a wound.

Expandable hemostat composed of oxidized cellulose

Provided is a method for purifying α-thrombin and for quantifying α-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified α-thrombin. The method can also be used for purification and/or quantification of β-thrombin.

Method for purifying and quantifying thrombin and its degradation polypeptides

Provided are pharmaceutical foam compositions comprising a peptone, a peptide hydrolysate or an enzymatically-hydrolyzed protein prepared by enzymatic hydrolysis of a full-length protein; methods of preparation and uses thereof.

Stable pharmaceutical foam

Provided are pharmaceutical compositions comprising an anion exchanger and a calcium salt; methods for inducing hemostasis at a site of bleeding by applying to the site of bleeding an effective amount of the compositions; and methods of preparation of the compositions.

Hemostatic composition comprising an anion exchanger and a calcium salt

Provided is a method for purifying &#x3b1;-thrombin and for quantifying &#x3b1;-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified &#x3b1;-thrombin. The method can also be used for purification and/or quantification of &#x3b2;-thrombin.

Provided herein is a plasma-supplemented fibrinogen and/or fibrin formulation, method for the preparation and use thereof.

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Rehovot, Israel

Tamar Auerbach-Nevo