Bio-rad Laboratories, Inc.

Tal Rosenzweig

Nenad M Kircanski

Amir Sadri

Daniel Y Chu

Paul J Patt

Kun Guo

Alwin Wan

Edmond Young

Boaz Ran

Ariel Notcovich

James W Hillendahl

Yochanan Uri

Ariel Shemesh

Nenad Kircanski

Michael Kanevsky

Daniel Konstantinou

Barak Abraham Liraz

Amir M Sadri

A method for efficiently manufacturing and fabricating microfluidic chips, where a base mold is formed to have positive-relief features used to cast an intermediary template chip with negative-relief features having dimensions of a scale in the micron range. The intermediary template chip is used to case a production mold, which is formed of a reinforced epoxy resin that, once hardened into a solid epoxy member, can withstand the structural pressures of a CNC machining system. The production mold can be refined by a CNC machining, where the refined production mold is then used to cast production chips to be used as microfluidic chips.

Epoxy mold making and micromilling for microfluidics

Microscale fluidic devices and components thereof having a fluid retention groove, as well as systems and methods related thereto. The fluid retention groove facilitates uniform bonding of microfluidic device components.

Microscale fluidic devices and components having a fluid retention groove

Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads.

On-demand particle dispensing system

Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads. The systems may include a shaped focusing chamber and/or a branched diverting mechanism.

Multidimensional hydrodynamic focusing chamber

An SPR or other optical resonance based analysis system in which, light is provided at multiple angles to a specimen and then the light modified by the specimen is processed to select only some of the light. Optionally, the processing selects light at a particular incidence angle. Optionally, the detection is by imaging of the light on a 2D imager array.

Optical resonance analysis using a multi-angle source of illumination

Growing community of inventors

Toronto, Canada

Tal Rosenzweig