The University of Tokyo

Genefrontier Corporation

Subaru Corporation

Sharp Nec Display Solutions, Ltd.

Mitsubishi Tanabe Pharma Corporation

Post Genome Institute Co., Ltd.

Takuya Ueda

Takashi Kanamori

Kanehisa Kojoh

Yoshihiro Shimizu

Mikiko Nakamura

Kumiko Tsuihiji

Yuki Hayami

Tomoe Fuse

Shizue Kato

Shizue Katoh

Akira Miyakoshi

Yasuhiro Fujino

Kou Sasaki

Kouichi Wada

Yoshikatsu Nishiyama

Risako Fujita

Kotomi Oda

Akio Inoue

An information processing device is configured to determine whether an animal is suffering from motion sickness. The animal is an animal other than an occupant who rides in a mobile object. The information processing device includes one or more processors, and one or more memories communicably coupled to the one or more processors. The one or more processors are configured to acquire an image captured by a camera configured to capture an image of the animal. The one or more processors are configured to, based on behavior data of the animal, determine whether the animal is suffering from motion sickness. The behavior data is externally observable from the captured image.

Information processing device for determining motion sickness of an animal

An information processing apparatus configured to determine a condition of an animal that is other than a human and moving on a mobile body. The information processing apparatus includes one or more processors and one or more memories communicatively coupled to the one or more processors. The one or more processors are configured to execute: obtaining a first vibration detection result indicating vibration of the animal and a second vibration detection result indicating vibration in a surrounding environment of the animal; and determining the condition of the animal based on the first vibration detection result, the second vibration detection result, and a vibration pattern that is accumulated in a database.

Information processing apparatus for assessing animal condidtion in vehicle

A projection-type display device includes: an operation signal detector, configured to receive an operation signal that indicates adjustment content of a projected image that was instructed by way of an operation unit; an installation state detector, configured to detect, as an installation state of the projection-type display device, a first state and a second state that is rotated 90 degrees from the first state around an axis that is parallel to an optical axis of a projection lens; and a controller that, upon detecting a signal that corresponds to a first direction by way of the operation signal detector in the first state and the second state, adjusts the projected image by causing the projected image to shift in the first direction, or adjusts the projected image by causing a correction-object site in the projected image to move in the first direction.

Projection-type display device and method for adjusting a projected image

This projection-type display device has: an operation signal detection unit that receives operation signals that indicate adjustment content of a projected image, the adjustment content having been instructed by way of an operation unit; an installation state detection unit that detects, as the installation state of the projection-type display device, a first state and a second state realized by rotating 90 degrees around an axis parallel to the optical axis of the projection lens; and a control unit that, upon detecting a signal that corresponds to the first direction by way of the operation signal detection unit in the first state and the second state, adjusts a projected image by shifting the projected image in the first direction or by moving a correction-object site in the projected image in the first direction.

The polynucleotide construct of (1) or (2) below is used to perform ribosome display, CIS display and/or mRNA display in order to screen a Fab against an antigen of interest: (1) a polynucleotide construct which monocistronically comprises a ribosome-binding sequence, Fab first chain-coding sequence, linker peptide-coding sequence, Fab second chain-coding sequence and scaffold-coding sequence in this order, and further comprises at its 3'-end a structure necessary for maintaining a complex with the Fab encoded by itself; and (2) a polynucleotide construct which comprises a Fab first chain-expressing cistron and a Fab second chain-expressing cistron each containing a ribosome-binding sequence, a Fab first chain-coding sequence or Fab second chain-coding sequence, and a scaffold-coding sequence in this order, the first Fab-expressing cistron further comprising at its 3&#x2032;-end a ribosome stall sequence, said Fab second chain-expressing cistron further comprising at its 3&#x2032;-end a structure necessary for maintaining a complex with the Fab encoded by itself.

Polynucleotide construct capable of displaying fab in a cell-free translation system, and method for manufacturing and screening fab using same

According to the present invention, a composition possessing cell-free protein synthesis activity with reduced contaminating lipopolysaccharide, and a method for producing a protein using the same are provided. When ribosome display is performed using the composition and method for protein production of the present invention, the background that is caused by non-specific binding is reduced, so that a nucleic acid that encodes the desired polypeptide can be selected with high accuracy and high efficiency.

Composition for synthesizing protein with reduced lipopolysaccharide contamination, method for producing protein using said composition

The present invention provides a method of producing a maturated oligonucleotide library, including a step of obtaining a terminal-modified product of a maturation target oligonucleotide library, including adding a tag sequence to the 5' terminus of the maturation target oligonucleotide library and an arrest sequence, which stalls translation elongation on a ribosome, to the 3&#x2032; terminus of the maturation target oligonucleotide library, a step of transcribing the terminal-modified sequence product to give a transcript, and a step of in vitro translation for translating the transcript in vitro, wherein the maturation target oligonucleotide library is a random oligonucleotide library.

High-speed maturation method for an oligonucleotide library for the purpose of preparing a protein library

The present invention relates to a reaction system whereby a peptide produced in an in vitro peptide synthesis system can be efficiently isolated at a high purity from the reaction system. Thus the present invention is a process for producing a peptide or a peptide derivative by using a reaction system of transcribing a DNA into an RNA and then translating the RNA produced or a reaction system of translating an RNA in vitro wherein at least one protein component of the reaction system is labeled with a first substance which adheres to a second substance, and said second substance is used as an adsorbent for capturing said labeled protein components after translating.

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Tokyo, Japan

Takuya Ueda