Fujisawa Pharmaceutical Company, Ltd.

Takumi Yatabe

Hitoshi Yamazaki

Hirokazu Tanaka

Norihiko Shimazaki

Yoshikuni Itoh

Masashi Hashimoto

Teruo Kyoto Oku

Yoshio Kawai

Seiji Hashimoto

Natsuko Kayakiri

Takayuki Inoue

Hitoshi Hamashima

Toshiro Iwamoto

Kousei Yoshihara

Peptide compounds for treatment of no-mediated diseases

Benzofuran derivatives useful as inhibitors of bone resorption

This invention relates to certain 1-heterocycloalkylquinazolin-2,3-dione derivatives, certain pharmaceutically acceptable salts thereof, the process of making those compounds, and the method of using the compounds. The compounds and compositions display effects on the peripheral or central nervous system.

Quinazoline derivatives and their preparation

A compound of the formula: ##STR1## in which R.sup.1 and R.sup.2 are each hydrogen, halogen, nitro, amino, protected amino, hydroxyamino, lower alkyl, hydroxy, protected hydroxy, sulfamoyl, carboxy, protected carboxy, mercapto, optionally substituted heterocyclic-carbonyl, optionally substituted heterocyclic-(lower)alkyl, lower alkylthio, hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,

Compounds of the formula: ##STR1## are described wherein R.sup.1, R.sup.2, R.sup.3 and A are described in the claims. These compounds show significant dopamine receptor agonist activity.

Quinazoline derivatives

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Tsukuba, Japan

Takumi Yatabe