Canon Kabushiki Kaisha

Astellas Pharma Gmbh

Takeyuki Nagashima

Hisao Hamaguchi

Kazuyuki Kuramoto

Yuki Sawada

Tomoyuki Saito

Keiichi Takashima

Kenichi Kawaguchi

Eiji Kawaminami

Hiroki Koyano

Hidenori Azami

Hitoshi Osaka

Sunao Imada

Kenta Hara

Kei Ohnuki

Tomoyoshi Imaizumi

Takashi Shin

Mitsuaki Okumura

Kohei Inamura

Hideyuki Watanabe

Keiichiro Yuasa

Hiroki Ishioka

Shigetoshi Kikuchi

Koichiro Matsuzaki

Tomohiro Yoshinari

[Problem] To provide a compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer. [Means for resolution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a quinazoline compound has an excellent degradation-inducing action on a G12D mutant KRAS protein and a G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The quinazoline compound or a salt thereof of the present invention can be used as a therapeutic agent for pancreatic cancer.

Quinazoline compound for inducing degradation of G12D mutant KRAS protein

The present disclosure is directed to providing an information processing apparatus in which a management application is executed sets a first schedule for determining timing for transmitting an instruction to shift to a predetermined power supply state in which a request via a network fails to a management target device and a second schedule for determining timing for transmitting a request according to a setting of a security policy to the management target device via the network, and executes processing so that timing for transmitting a request based on the second schedule regarding the setting of the second schedule does not overlap with a period during which a request fails due to an instruction to be transmitted based on the first schedule.

Information processing apparatus, method, and storage medium

A management apparatus transmits information of a manager control task to each agent service, manages an execution result of processing executed in each network device, which is a processing target, for each of the sub-tasks generated at each agent service based on the manager control task, and transmits a response indicating whether execution of a sub-task is permitted based on an inquiry from each agent service to control the number of sub-tasks executed in parallel in the same time slot.

System, management apparatus, method, and storage medium

A management server receives selection of a setting item to be a monitoring target from setting information that can be set for a device, extracts, as monitoring data, setting information corresponding to the selected setting item, generates a monitoring task in which a device to be a monitoring target using the monitoring data, a monitoring setting, and a monitoring schedule are set, and saves the monitoring data corresponding to the monitoring task. Meanwhile, when the setting of a device is monitored using a security policy, not monitoring data but a policy version corresponding to setting information for use in monitoring is selected to generate a monitoring task.

Monitoring apparatus and method

A management apparatus for executing a management application for managing network devices on a network, configured to register, as a function of the plug-in for adding a service to the management application, remote tasks having different priorities in an execution waiting task queue according to the priorities, and to sequentially execute the first one of the remote tasks registered in the execution waiting task queue.

Management apparatus and management method for management apparatus

Compounds of formula (I) and salts thereof: wherein the variables are defined herein, are useful for the treatment of breast cancer.

Bicyclic nitrogen-containing aromatic heterocyclic amide compound

A management device manages management information including a type and a version of a driver installed on each client device and an output destination, specifies client devices on which a driver corresponding in type to the peripheral device has been installed with reference to the management information when the driver to be utilized in the client devices is changed in accordance with the change in information of the peripheral device, extracts a client device in which the peripheral device is set as the output destination from among the specified client devices with reference to the management information, and transmits an instruction for installing a driver to be changed to the extracted client device.

Management device, management device control method, and storage medium

An information processing apparatus is used in a network environment including a plurality of printing apparatuses and a plurality of client devices which form printing data for realizing a printing processing in the plurality of printing apparatuses. Regarding an association between printing apparatus and driver constituting a selection unit at the time of distributing drivers corresponding to the printing apparatuses, from the information processing apparatus to the client devices, it is possible to prepare and select associations of [N:1], [1:N], and [N:N]. As a result, it is possible to mitigate erroneous association selection and to achieve further simplification in procedures at the time of selection, which leads to a reduction in total cost of ownership (TCO).

Information processing apparatus, information processing method, and program

A server apparatus manages a device driver for enabling any of a plurality of devices to which a plurality of client apparatuses are connected on a network. The server apparatus comprises a storage unit that stores, for each device, a device driver that can be installed to the device in association with the device, a generating unit that generates different tasks for any of the stored device drivers, a creating unit that creates a schedule for executing the generated tasks, and an executing unit that executes the generated tasks based on the created schedule.

Information processing apparatus for controlling installation, method for controlling the apparatus and control program for executing the method

A driver management unit of a management server develops non-[1:1] type association information generated in a batch association creation mode into [1:1] type association information. On the other hand, the driver management unit stores association information created in an ordinary association creation mode in a data storage unit without performing the development. Further, the driver management unit transmits a list of the association information stored in the data storage unit to a client in response to a request, and distributes a driver selected from the list to the client in such a way as to create a logical printer of a device that corresponds to the association information selected from the list for the client.

Server apparatus and method for the same

A client is used in an environment in which a printing method for causing a device to print printing data via a print server coexists with a printing method for transmitting print data to the device without the intervention of the print server for printout. If it is determined that a printer driver to be set up on the local printer is a newer version than that of a printer driver for a network printer and is shared therewith, a printer driver to be set up on the local printer is set up, and setting processing regarding a printer driver on the print server so as to cause the network printer to operate normally is performed.

Information processing apparatus, and information processing method

A driver management apparatus includes a receiving unit configured to receive a network entry message sent by unicast according to a search protocol for one-to-one connection from one of a plurality of devices connected to a network, a determination unit configured to determine a capacity to install a driver according to the search protocol for one-to-one connection of a device connected to the network, and a processing unit configured to perform processing for installing, on a client terminal apparatus connected to the network, a driver for operating a device that has sent the network entry message. The processing unit is configured to perform different processing operations for installing the driver for operating the device with respect to respective devices having different capacities according to the capacity determined by the determination unit.

Driver management apparatus and method therefor

When an information processing apparatus has moved from one sub-area to another sub-area, anycast is performed to a plurality of management servers using an IP address for anycast in accordance with network management information. Network management information is acquired from a management server which has responded to the anycast. The acquired network management information and installed device driver information are analyzed. If there is a device driver for a device belonging to the sub-area managed by the management server which has responded, one of the devices belonging to the other sub-area is selected as a default device. This arrangement enables the selection of an appropriate default printer when a client has moved from a network environment managed by one management server to another network environment managed by another management server.

Information processing apparatus, information processing apparatus control method, and storage medium storing computer program

A driver management apparatus includes a receiving unit configured to receive a network entry message sent by unicast according to a search protocol for one-to-one connection from a device connected to a network, a determination unit configured to determine an operation environment in which the device executes a job sent from a client apparatus connected to the network, and an installation unit configured to install a driver for operating the device that has sent the network entry message according to the operation environment determined by the determination unit.

A server apparatus manages a device driver for enabling any of a plurality of devices to which a plurality of client apparatuses are connected on a network. The server apparatus stores, for each client apparatus, a device driver that can be installed to the client apparatus in association with the client apparatus. In addition, the server apparatus creates a driver install task for installing any of the device drivers to any of the client apparatuses, and an agent install task for installing an agent that inquires any of the client apparatuses to install a device driver.

Growing community of inventors

Tokyo, Japan

Takeyuki Nagashima