Terumo Kabushiki Kaisha

Takeyuki Moriuchi

Yusuke Komata

Fumihiko Chai

Hiroya Sato

Masao Takinami

Ryokei Aikawa

Shouji Ochiai

Hidenori Fujiwara

Takayuki Sugiyama

Yuma Hayashida

Hiroaki Satow

A blood glucose measurement reagent includes glucose dehydrogenase; a chromogenic indicator; and an aromatic hydrocarbon having at least one sulfonic acid group.

Blood glucose measurement reagent, sensor chip, and blood glucose meter set

Provided is a means capable of measuring an analyte concentration with high accuracy without requiring fractionation of a biological component. The present invention relates to a method for measuring an analyte concentration in a specimen, including (1) preparing the specimen, (2) mixing a coloring reagent, an oxidoreductase, and a light-scattering adjustment reagent with the specimen to obtain an analysis sample having substantially the same scattered light as the specimen, and (3) measuring the analyte concentration by using the analysis sample.

Method, reagent, and chip for measuring analyte concentration in specimen

Blood glucose test strip

A blood glucose level measuring chip exhibits excellent blood spreading ability and can maintain a reaction rate of blood with a reagent, even where the blood has a high hematocrit value (Ht). The blood glucose level measuring chip includes a blood glucose level measuring reagent including a supply port through which blood is supplied, a flow path having the supply port formed at one end of the flow path, and a blood glucose level measuring reagent containing an aromatic hydrocarbon having at least one sulfonic acid group disposed on an inner wall defining the flow path, wherein a ratio A/B is 3.7 mmol/L or more to 184.8 mmol/L when A (mmol) represents the total molar amount of aromatic hydrocarbons contained in the blood glucose level measuring reagent, and B (L) represents a volume of a region in which the blood glucose level measuring reagent and the blood are dissolved.

Blood glucose level measuring chip and blood glucose level measuring device set

A composition for detecting an analyte in a blood sample includes: a coloring reagent; an oxidoreductase; and a refractive index adjuster.

Method, composition, and chip for detecting analyte in blood sample

Blood glucose meter

A method for detecting an analyte in a blood sample includes dissolving a refractive index adjuster in the blood sample to obtain an analysis sample in which a difference in refractive index between a red blood cell and an extra-red blood cell fluid is reduced and detecting the analyte using the analysis sample.

A blood glucose measurement reagent includes: an enzyme having glucose as a substrate; a mediator; a chromogenic indicator; and an aromatic hydrocarbon having at least one sulfonic acid group. A sensor chip includes: a supply port through which blood is suppliable; a flow path having the supply port formed at one end thereof; and a reagent located in the flow path, the reagent being the blood glucose measurement reagent; wherein the sensor chip is mountable on a blood glucose meter for measuring blood glucose in the blood.

Provided is a component measuring apparatus configured to determine a functional form that describes wavelength characteristics of a variation attributable to scattering (S (&#x3bb;)). The apparatus then determines unknown one or more coefficients (p, q) based on a first relational expression that involves a variation attributable to absorption (H (&#x3bb;)) and a group of second relational expressions that do not involve variations attributable to absorption (H (&#x3bb;), H (&#x3bb;), H (&#x3bb;)). The apparatus then corrects an absorbance measured at an arbitrary wavelength (&#x3bb;) using a function where the one or more coefficients (p, q) are applied to the functional form so as to reduce or eliminate at least the effects of scattering of light.

Growing community of inventors

Yamanashi, Japan

Takeyuki Moriuchi