Mitsubishi Gas Chemical Company, Inc.

Merck Sharp + Dohme Corp.

Msd K.k.

Taketo Ikeno

Hideyuki Sato

Tomoo Tsujimoto

Masayuki Katagiri

Umi Yokobori

Makoto Tsubuku

Ryuji Hasemi

Takashi Kobayashi

Yoshihiro Kato

Masashi Kawasaki

Shinji Kato

Atsushi Okamoto

Masanobu Sogame

Yuuichi Sugano

Yoshinori Mabuchi

Fuyuki Yamamoto

Yaling Wang

Keita Tokuzumi

Sachin Lohani

Kenji Arii

Kenj Arii

Hisaki Kojima

Tetsuya Shimo

Shuntaro Furukawa

Wataru Minagawa

Naotaka Sawada

Provided is a urethane (meth)acrylate capable of achieving high strength and high elongation, as well as a method for manufacturing a urethane (meth)acrylate, a curable composition, a cured article, and a method for manufacturing a cured article. The urethane (meth)acrylate contains a structural unit derived from polycarbonate diol, a structural unit derived from polyisocyanate, and a hydroxy group-containing (meth)acrylate-derived group, the polycarbonate diol containing one or more types of structural unit represented by formula (1) wherein each of R, R, Rand Rindependently represents an aliphatic hydrocarbon group having 1 to 6 carbon atoms. 

Urethane (meth)acrylate, method for manufacturing urethane (meth)acrylate, curable composition, cured article, and method for manufacturing cured article

Provided is a diol that excels in thermal stability; and, a method for manufacturing a diol, a di(meth)acrylate, and a method for manufacturing a di(meth)acrylate. The diol represented by the formula (1) below; wherein each of Rand Rindependently represents a hydrocarbon group; and each Rindependently represents a hydrogen atom, hetero atom-containing group, halogen atom, straight chain alkyl group having 1 to 6 carbon atoms, branched alkyl group having 3 to 6 carbon atoms or, aryl group-containing group having 6 to 12 carbon atoms. 

Diol, method for manufacturing diol, di(meth)acrylate, and method for manufacturing di(meth)acrylate

The present invention relates to a diacrylate compound represented by general formula (1), a composition thereof, and a cured product of the compound/composition.  In the formula, R denotes a hydrogen atom or a methyl group; R, R, R, and Reach independently denote a Clinear or branched alkyl group, with the proviso that R, R, R, and Rare not all methyl groups. The present invention provides: a novel diacrylate compound which can provide a cured product having an excellent balance of physical properties such as low curing shrinkage, flexibility, resistance to bending, and low curling properties, and which can be used as a photo- or thermal-radical polymerizable monomer; a composition of the compound; and a cured product of the compound/composition.

Diacrylate compound, composition thereof, and cured product thereof

The invention provides a triacrylate compound represented by the following formula (1). In the formula, each R is independently a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or a halogen atom, Rand Rare each independently a linear or branched alkyl group having 1 to 6 carbon atoms, and Ris a linear or branched alkyl group having 1 to 6 carbon atoms or a hydroxymethyl group.

Triacrylate compounds and methods for producing the same, and compositions

The present invention relates to a limited composition containing a diacrylate compound represented by general formula (1).  In the formula, R denotes a hydrogen atom or a methyl group. The present invention provides a diacrylate-compound-containing composition which provides a cured product having excellent physical properties such as low curing shrinkage, flexibility, resistance to bending, and low curling properties, and which can be used as a photo- or thermal-radical polymerizable composition and a cured product of the composition.

Diacrylate-compound-containing composition and cured product thereof

A curable resin composition which can achieve a cured product in which the generation of cracks upon curing is suppressed and which has both a low thermal expansion rate and a low water absorbability is provided. The curable resin composition comprises: at least a cyanate ester compound (A) represented by the following formula (I); a metal complex catalyst (B); and an additive (C), wherein the additive (C) contains any one or more selected from the group consisting of a compound represented by the following general formula (II), a compound represented by the following general formula (III), and a tertiary amine. 

Curable resin composition and cured product thereof

A method for efficiently producing a cyanogen halide with suppressed side effects, and a method for producing a high-purity cyanate ester compound at a high yield includes contacting a halogen molecule with an aqueous solution containing hydrogen cyanide and/or a metal cyanide, so that the hydrogen cyanide and/or the metal cyanide is allowed to react with the halogen molecule in the reaction solution to obtain the cyanogen halide, wherein more than 1 mole of the hydrogen cyanide or the metal cyanide is used based on 1 mole of the halogen molecule, and when an amount of substance of an unreacted hydrogen cyanide or an unreacted metal cyanide is defined as mole (A) and an amount of substance of the generated cyanogen halide is defined as mole (B), the reaction is terminated in a state in which (A):(A)+(B) is between 0.00009:1 and 0.2:1.

Method for producing cyanogen-halide, cyanate ester compound and method for producing the same, and resin composition

There is provided a novel dicyanatophenyl-based difunctional cyanate ester which is in a liquid form at ordinary temperature and can obtain a cured product having an excellent low thermal expansion rate. There is disclosed a cyanate ester compound represented by the following formula (I): (wherein Rrepresents a hydrocarbon group having 2 to 20 carbon atoms).

Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof

There is provided a novel cyanate ester compound that can provide a cured product possessing excellent heat resistance. The cyanate ester compound is represented by general formula (1): wherein R1 represents an aromatic substituent having 6 to 10 carbon atoms or an alkyl group having 1 to 20 carbon atoms; Rx1's each independently represent a hydrogen atom, an alkyl or alkoxy group having 1 to 20 carbon atoms, or a halogen; Ry1's each independently represent a hydrogen atom, an alkyl or alkoxy group having 1 to 20 carbon atoms, or a halogen; m is an integer of 0 to 4; and n is an integer of 0 to 4.

Cyanate ester compounds and cured products thereof

The present invention relates to a process for producing a hydrate of 3-(2,6-dichlorophenyl)-4-imino-7-[(2'-methyl-2&#x2032;,3&#x2032;-dihydro-1&#x2032;H-spiro[cyclopropane-1,4&#x2032;-isoquinolin]-7&#x2032;-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one (Compound A) or of a pharmaceutically acceptable salt of Compound A and a crystalline form of Compound A or of a pharmaceutically acceptable salt of Compound A, which are useful in the field of treatment of various cancers as a kinase inhibitor, especially as a Weel kinase inhibitor.

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Niigata, Japan

Taketo Ikeno