Fujitsu Corporation

Japan Science and Technology Agency

Takeshi Terada

Kenichi Kawarai

Yasuhiro Ooba

Masahiro Mizuta

Kohji Seio

Mitsuo Sekine

Yasutaka Ohno

The purpose of the present invention is to provide a compound that specifically binds to the base sequence of a double-stranded nucleic acid molecule. The compound can reduce the electrochemical signal/noise ratio (S/N) in electrochemical detection, and as a result, the detection sensitivity (precision) will be greatly improved so as to enable the determination of an ultratrace amount of nucleic acid molecule. The present invention relates to a ferrocene compound represented by the following general formula (I): wherein 'A' represents a divalent ferrocene-containing linker or ferrocene-1,1'-yl, Rrepresents a hydrogen atom or alkyl; 'n' and &#x201c;m&#x201d; represent any natural numbers; and &#x201c;V&#x201d; and &#x201c;X&#x201d; represent the pyrrole-imidazole-polyamide (PIPA); to a ligand consisting of said ferrocene compound for sequence-specific detection of double-stranded nucleic acid molecules; to a method for electrochemical detection of double-stranded nucleic acid molecules 8 with the use of said ligand; and to an apparatus or device for the electrochemical detection with the use of said ligand.

Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule

A packet insertion interval control system includes a counting unit ( ), having a first bit field for managing an insertion interval of a management packet required to be cyclically inserted and a second bit field for specifying a logic path for forwarding the management packet, for executing such a counting operation as to periodically cycle the first bit field and the second bit field, and a control unit ( ) for executing control for specifying, when a count value indicated by the first bit field of the counting unit is a predetermined value, the logic path for forwarding the management packet on the basis of a count value indicated by the second bit field of the counting unit, and for inserting the management packet into the specified logic path. With this architecture, it is feasible to restrain an increase in quantity of the hardware and flexibly correspond to changes in the number of connections (number of channels) and the cell insertion interval (packet insertion interval) per communication system.

Packet insertion interval control system and packet insertion interval control method

Growing community of inventors

Yokohama, Japan

Takeshi Terada