Kowa Company Limited

Takeshi Oda

Toshihito Mori

Akio Iwasaki

Takeo Deushi

Kazuhiro Kamiya

Toshimi Mizoguchi

Hisakatsu Ito

Takafumi Kunieda

Masahito Nakayama

Takashi Yamaguchi

Toshito Mori

Masahoto Nakayama

Novel antibiotics of the following structure ##STR1## wherein R represents a moiety selected from the group consisting of hydrogen, --COCH.sub.2 NH.sub.2, --COCH.sub.2 NHCONH.sub.2 and --COCH.sub.2 NHCHO; process for preparation thereof; and biologically pure culture for use therein.

Biologically pure culture

Novel antibiotics, process for preparation thereof and biologically pure

Antibiotics of the KA-6606 series and pharmaceutical compositions thereof

Novel .beta.-D-ribofuranosyl (1 .fwdarw. 5), O-[.alpha.-D-2-amino(or 2-acylamino)-2, 3-dideoxy-glucopyranosyl (1 .fwdarw. 4) ] 1, 3-diamino (or 1, 3-diacylamino)-1, 2, 3-trideoxy-myoinositols and their acid salts. These compounds are useful either as antibiotics or as intermediates for their synthesis. The compound can be produced by treating an O-.alpha.-L-2, 6-diacylamino-2, 6-dideoxyidopyranosyl (1 .fwdarw. 3), .beta.-D-ribofuranosyl (1 .fwdarw. 5), O-[.alpha.-D-2-acylamino-2, 3-dideoxy-glucopyranosyl (1 .fwdarw. 4)] 1, 3-diacylamino-1, 2, 3-trideoxy-myoinositol with periodic acid or its salts, reacting the resulting compound with an amine, and optionally deacylating the product.

Novel aminocyclitols and process for production thereof

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Kodaira, Japan

Takeshi Oda