Nissan Chemical Industries Limited

Nissan Chemical Corporation

Takeshi Mita

Mitsuaki Komoda

Manabu Yaosaka

Takamasa Kikuchi

Takashi Mizukoshi

Eitatsu Ikeda

Ken-ichi Toyama

Motoyoshi Iwasa

Yuki Furukawa

Hotaka Imanaka

Shinji Takii

Hidehito Kuwahara

Kazushige Maeda

Yoshihide Masuzawa

Hideo Suzuki

Toshiaki Takeyama

Keisuke Tsuji

Kazuhiro Yamagishi

Masami Hanaue

Mitsutaka Tomizawa

Miho Asahi

Masao Nishikubo

Masaki Kobayashi

Koichi Maeda

Kunimitsu Nakahira

Yoshinori Ochiai

Kazutaka Matoba

Hideki Takamatsu

Yukihiro Maizuru

Hiroto Matsui

Rika Miyachi

Gozyo Sakata

Hiroaki Takahashi

Takahiro Kagami

Masashi Ohno

Kenichi Toyama

Kotatsu Matsubara

Yusuke Nanjo

Taichi Shimomiya

Youko Yamada

Heike Williams

Anja Regina Heckeroth

Hartmut Zoller

Juergen Lutz

Ken-Ichi Toyama

Christina Mertens

A substituted alkenylbenzene compound of formula (4): wherein Xis selected from the group consisting of a halogen atom, &#x2014;SF, C-Chaloalkyl, hydroxy C-Chaloalkyl, C-Calkoxy C-Chaloalkyl, C-Chalocycloalkyl, C-Chaloalkoxy, C-Chaloalkoxy C-Chaloalkoxy, C-Chaloalkylthio, C-Chaloalkylsulfinyl and C-Chaloalkylsulfonyl; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C-Calkyl, C-Chaloalkyl, C-Calkoxy and C-Calkylthio; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, C-Calkyl, C-Calkoxy and C-Chaloalkoxy; Ris &#x2014;C(R)(R)R, where Rand Rindependently of each other are a halogen atom, or Rand Rtogether form 3- to 6-membered ring together with the carbon atom bonding them by forming a C-Chaloalkylene chain, and Ris selected from the group consisting of a hydrogen atom, halogen atom, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy and C-Chaloalkylthio, with a proviso that in case where Xis a fluorine atom, chlorine atom or trifluoromethyl, and both Xand Xare a hydrogen atom, in case where both Xand Xare fluorine atom and Xis a hydrogen atom, and in case where both Xand Xare trifluoromethyl and Xis a hydrogen atom, Ris a hydrogen atom, chlorine atom, bromine atom, iodine atom, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy or C-Chaloalkylthio.

Isoxazoline-substituted benzamide compound and pesticide

A substituted alkenylbenzene compound of formula (4): wherein Xis selected from the group consisting of a halogen atom, &#x2014;SF, C-Chaloalkyl, hydroxy C-Chaloalkyl, C-Calkoxy C-Chaloalkyl, C-Chalocycloalkyl, C-Chaloalkoxy, C-Chaloalkoxy C-Chaloalkoxy, C-Chaloalkylthio, C-Chaloalkylsulfinyl and C-Chaloalkylsulfonyl; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C-Calkyl, C-Chaloalkyl, C-Calkoxy and C-Calkylthio; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, C-Calkoxy and C-Chaloalkoxy; Ris &#x2014;C(R)(R)R, where Rand Rindependently of each other are a halogen atom, or Rand Rtogether form 3- to 6-membered ring together with the carbon atom bonding them by forming a C-Chaloalkylene chain, and Ris selected from the group consisting of a hydrogen atom, halogen atom, C-Chaloalkyl, C-Chaloalkoxy and C-Chaloalkylthio, with a proviso that in case where Xis a fluorine atom, chlorine atom or trifluoromethyl, and both Xand Xare a hydrogen atom, in case where both Xand Xare fluorine atom and Xis a hydrogen atom, and in case where both Xand Xare trifluoromethyl and Xis a hydrogen atom, Ris a hydrogen atom, chlorine atom, bromine atom, iodine atom, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy or C-Chaloalkylthio.

A substituted alkenylbenzene compound of formula (4): wherein Xis selected from the group consisting of halogen atom, &#x2014;SF, C-Chalo alkyl, hydroxy C-Chaloalkyl, C-Calkoxy C-Chaloalkyl, C-Chalocycloalkyl, C-Chaloalkoxy, C-Chaloalkoxy C-Chaloalkoxy, C-Chaloalkylthio, C-Chaloalkylsulfinyl and C-Chaloalkylsulfonyl; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C-Calkyl, C-Chaloalkyl, C-Calkoxy and C-Calkylthio; Xis selected from the group consisting of a hydrogen atom, halogen atom, cyano, C-Calkyl, C-Calkoxy and C-Chaloalkoxy; Ris &#x2014;C(R)(R)R, where Rand Rindependently of each other are a halogen atom, or Rand Rtogether form 3- to 6-membered ring together with the carbon atom bonding them by forming a C-Chaloalkylene chain, and Ris selected from the group consisting of a hydrogen atom, halogen atom, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy and C-Chaloalkylthio, with a proviso that in case where Xis a fluorine atom, chlorine atom or trifluoromethyl, and both Xand Xare a hydrogen atom, in case where both Xand Xare fluorine atom and Xis a hydrogen atom, and in case where both Xand Xare trifluoromethyl and Xis a hydrogen atom, Ris a hydrogen atom, chlorine atom, bromine atom, iodine atom, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy or C-Chaloalkylthio.

Provided is a novel pesticide, particularly a fungicide and a nematicide. An alkynyl pyridine-substituted amide compound represented by formula (I), its N-oxide or a salt thereof, and a pesticide containing it. [In the formula, Gis a structure represented by G-1a, G-3a, G-27a, etc.; Xis a halogen atom, difluoromethyl, trifluoromethyl, etc.; Yis a halogen atom, etc.; Y, Y, Rand Rindependently represent a hydrogen atom, etc.; Ris a hydrogen atom, a halogen atom, methyl, methoxy, etc.; Ris a hydrogen atom, a halogen atom, etc., or Rand Rtogether form an alkylene chain thereby to form a cyclopropyl group together with the carbon atom to which Rand Rare bonded, or Rand Rtogether form C-Calkylidene or C-Chaloalkylidene; Ris a hydrogen atom, methyl, etc.; and Ris C-Calkyl, C-Ccycloalkyl, C-Calkoxy(C-C)alkyl, etc.] 

Alkynyl pyridine-substituted amide compound and pesticide

To provide a novel pesticide, especially a fungicide and a nematocide. An oxime-substituted amide compound represented by the formula (I) or its salt, and a pesticide containing it: wherein Gis a structure represented by G-1 or the like, Gis a structure represented by G-2 or the like: W is an oxygen atom or the like, Xis a halogen atom, methyl, trifluoromethyl or the like, each of X, X, Xand Xis independently a hydrogen atom, a halogen atom or the like, each of Yand Yis independently a halogen atom, cyano, methyl, trifluoromethyl, C-Calkynyl or the like, each of Yand Yis independently a hydrogen atom, a halogen atom or the like, Ris C-Calkyl, C-Chaloalkyl, (C-C)alkyl substituted with R, C-Ccycloalkyl, C-Calkenyl or the like, each of Rand Ris independently a hydrogen atom, methyl or the like, Ris a hydrogen atom or the like, Ris C-Ccycloalkyl, phenyl, phenyl substituted with (Z)or the like, Z is a halogen atom or the like, and m is an integer of 1, 2 or 3.

Oxime-substituted amide compound and pest control agent

There is provided a novel agent for controlling harmful arthropods or nematodes that are parasites and hygienic pests for animals. An ecto- or endo-parasiticide for mammals or the like comprising as active ingredient, one or more selected from substituted benzamide compounds of formula (1) or salts thereof: wherein Ais C&#x2014;Xor nitrogen atom, etc., Aand Aare C&#x2014;H, etc., Ais C&#x2014;H or nitrogen atom, etc., G is G-2a, etc., W is oxygen atom or sulfur atom, Xis halogen atom, trifluoromethyl, etc., Xis hydrogen atom, halogen atom, trifluoromethyl, etc., Xis hydrogen atom, halogen atom, etc., Yis hydrogen atom, halogen atom, methyl, etc., Ris trifluoromethyl, etc., Ris E-3a, etc., Ris hydrogen atom, etc., p is an integer of 0 to 2.

Parasite- and hygienic pest-controlling agent

A method for manufacturing a crystal and a crystal of (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide and a method for manufacturing the crystal. It is elucidated that (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide that has a crystalline polymorph.

Crystalline polymorphs of isoxazoline compound and production method thereof

An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., W is oxygen atom or sulfur atom, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atom, C-Calkyl, etc., Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)OR, &#x2014;C(O)NHR, phenyl substituted with (Z), D-14, D-52, D-53, D-55 to D-59, etc., Ris C-Calkyl, etc., Ris C-Calkyl, etc., Ris hydrogen atom, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Calkyl, &#x2014;CHR, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., further when Ris &#x2014;CH&#x2550;NOR, &#x2014;C(O)ORor &#x2014;C(O)N(R)R, Rmay be hydrogen atom, Ris C-Chaloalkyl, etc., Ris cyano, &#x2014;OR, etc., Ris C-Calkyl, C-Chaloalkyl, C-Calkoxy C-Calkyl, C-Calkylthio C-Calkyl, C-Ccycloalkyl, C-Calkenyl, etc., Ris C-Calkyl, C-Chaloalkyl, &#x2014;C(O)Ror &#x2014;C(O)OR, etc., Ris C-Calkyl or C-Ccycloalkyl, etc., Z is halogen atom, cyano, nitro, C-Calkyl, C-Calkoxy, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

A substituted alkenylbenzene compound of formula (4): 

A substituted alkenylbenzene compound of formula (4): wherein Xis a halogen atom, &#x2014;SF, C-Chaloalkyl, hydroxy C-Chaloalkyl, C-Calkoxy C-Chaloalkyl, C-Chalocycloalkyl, C-Chaloalkoxy, C-Chaloalkoxy C-Chaloalkoxy, C-Chaloalkylthio, C-Chaloalkylsulfinyl or C-Chaloalkylsulfonyl; Xis a hydrogen, halogen, cyano, nitro, C-Calkyl, C-Chaloalkyl, C-Calkoxy or C-Calkylthio; Xis a hydrogen, halogen, cyano, C-Calkyl, C-Calkoxy or C-Chaloalkoxy; Ris &#x2014;C(R)(R)R, where Rand Rare a halogen, or Rand Rtogether form a- to-membered ring together with the carbon bonding them by forming a C-Chaloalkylene chain, and Ris a hydrogen, halogen, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy or C-Chaloalkylthio, with a proviso that where Xis a fluorine, chlorine or trifluoromethyl, and Xand Xare hydrogen, where Xand Xare fluorine and Xis a hydrogen, or where Xand Xare trifluoromethyl and Xis a hydrogen, Ris a hydrogen, chlorine, bromine, iodine, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy or C-Chaloalkylthio.

There is provided a novel pest control agent, particularly an insecticide or miticide. A substituted isoxazoline compound of General Formula (1): where A, Aand Aindependently are CH or N, etc., X, Xand Xare independently are H, a halogen atom, etc., Yis H, etc., Ris &#x2014;C(O)R, &#x2014;C(S)R, Ris &#x2014;C(R)(R)&#x2014;S(O)R, &#x2014;C(R)(R)&#x2014;S(O)(R)&#x2550;NR, etc., Ris H, etc., Ris CF, CClF, etc., Ris H, etc., Ris H, etc., Ris H, etc., Ris Calkyl, etc., Ris H, etc., r is an integer of 0-2, t is an integer of 0 or 1; and a pest control agent comprising the compound or the salt thereof.

Substituted isoxazoline compound and pest control agent

There is provided a novel pest control agent, particularly an insecticide or miticide. A substituted dihydroazole compound of General Formula (1) or a salt thereof: where A, A, Aand Aare independently C&#x2014;Y or N, Ais &#x2014;CH&#x2014;, etc., Gis a benzene ring, etc., Gis G-1, G-6, G-9, etc., X is a halogen atom, Chaloalkyl, etc., Z is methyl, &#x2014;NH, etc., Ris &#x2014;C(O)R, etc., Ris Calkyl, etc., Ris H, Calkyl, etc., Ris Chaloalkyl, etc., Ris H, cyano, methyl, etc., m is an integer of 1, 2, 3, etc., n is an integer of 0 or 1; and a pest control agent comprising the compound or the salt thereof.

Substituted dihydroazole compound and pest control agent

A pesticide, particularly an insecticide or an acaricide, including a substituted isoxazoline compound of formula (1) or a salt thereof: wherein A, Aand Aindependently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., L is &#x2014;N(R)&#x2014;, or &#x2014;CH(R)N(R)&#x2014;, etc., X is halogen atom, C-Chaloalkyl, etc., Y is halogen atom, C-Calkyl, etc., Ris &#x2014;C(O)R, &#x2014;C(O)OR, &#x2014;C(O)NHR, etc., Ris hydrogen atom, C-Chaloalkyl, &#x2014;C-Calkoxy C-Calkyl, cyano C-Calkyl, C-Calkenyl, C-Calkynyl, &#x2014;C(O)R, &#x2014;C(O)OR, etc., Ris C-Chaloalkyl, etc., m is an integer of 0 to 5, n is an integer of 0 to 4. The pesticide containing these compounds.

Isoxazoline compound and pesticide

Growing community of inventors

Funabashi, Japan

Takeshi Mita