Kao Corporation

Kanebo, Limited

Kanebo Cosmetics Inc.

Kanebo Ltd. and T. Hasegawa Co. Ltd.

Takeshi Ikemoto

Hiroko Nakatsugawa

Akinori Haratake

Shunsuke Yamazaki

Hiroyuki Nishio

Shintaro Inoue

Masaki Yoshida

Kyoko Miura

Hideyo Uchiwa

Mariko Hara

Syunsuke Yamazaki

Aya Komiya

Motoi Hayase

Junichi Matsui

Sachiyo Hirotsu

Tomohiro Yokota

Bunichi Okabe

Jun Sugita

Akira Fujita

Kazuo Ogino

Hiromi Minamino

Minoru Iwamoto

Yasushi Sumida

Yumiko Akazawa

Yoh-ichi Inoue

Masafumi Yakumaru

Yoshiko Iwamoto

Masayoshi Inui

Jun-ichi Matsui

Bun-ichi Okabe

Yurie Kobayashi

Mitsumasa Mitani

An antiwrinkle agent, lipolysis promoter, external composition for skin, and food and beverage composition having for an active ingredient thereof a compound represented by general formula (1): (wherein R represents a hydrogen atom or an acyl group having 2 to 20 carbon atoms)or an extract obtained from guinea ginger and/or an acylation treatment product of said extract.

Antiwrinkle agent, lipolysis promoter, external composition for skin and food and beverage composition

An antiwrinkle agent which is highly effective in alleviating wrinkles caused by the photoaging. The present invention relates to an antiwrinkle agent comprising an eugenyl glycoside.

Wrinkle-diminishing agent

The present invention provides an antiwrinkle agent and skin cosmetic composition having excellent alleviating effects on wrinkles appearing due to aging, and especially at exposed locations of skin, and a high degree of safety. The present invention relates to an antiwrinkle agent and skin cosmetic composition comprising a sclareol derivative represented by the following structural formula (1). 

Antiwrinkle agent and skin cosmetic composition

A skin cosmetic composition comprising the compound represented by the following formula (1): wherein Ris hydrogen and Ris hydrogen or glucose residue.

Dihydroxyphenyl compounds and glucoside compounds thereof

The present invention provides a method for enhancing epidermal permeability barrier function of the aged skin, which includes the step of externally administering to the aged skin an amount of a fumaric acid diester derivative expressed by the following general formula (1) as an active ingredient wherein Rrepresents a Calkylene group; Rand Reach represents a linear or branched Calkyl group; and n is an integer of 2 to 5.

Skin external agents and drugs

Skin external agent compositions and drugs characterized by containing fumaric acid diester derivatives represented by following general formula (1), wherein Rrepresents Calkylene; Rand Rrepresent each liner or branched Calkyl; and n is an integer of 2 to 5; which provide epidermal barrier function potentiating agents and skin external agent compositions having a high safety, quickly relieving epidermal permeation barrier function failures and having an effect of maintaining the skin in a cosmetologically healthy state; agents to be used together with HB-EFG expression inducing agents accelerating epidermal turnover, amphiregulin expression inhibitors regulating excessive epidermal proliferation, and retinoic acid or its derivative preventing skin chapping caused by retinoic acid or its derivative; and skin aging relieving agents capable of ameliorating depression in the skin metabolism and thinning in association with aging.

The present invention is a compound represented by the following formula (1) or (2):where one of Rand Ris hydrogen and the other one is hydrogen or glucose residue. The compound is effective for reforming obese constitution, suppressing or preventing obesity. It is also effective for skin whitening.

Noxious-insect repellent

The present invention provides a sustained-release aromatic, characterized in that the aromatic comprises at least one perfume derivative as an active component selected from glycosides of perfumes, phosphoric acid ester derivatives of perfumes, amino acid derivatives of perfumes and carboxylic acid derivatives of perfumes, and contains no enzyme or acid which decomposes the perfume derivative, wherein the perfume derivative is decomposed by bacteria usually present on the skin or yeast to release a perfume component to exhibit aroma. The present invention also provides a method for the detection of micro-organisms using the aforesaid sustained-release aromatic. As the sustained-release aromatic of the present invention releases a perfume component only when it is decomposed by micro-organisms such as bacteria usually present on the skin or yeast, the amount of perfumes to be used can be extremely reduced. The sustained-release aromatic of the present invention is also excellent in keeping aroma. The stability with the passage of time of the sustained-release aromatic of the present invention is much better than that of the prior art because the perfume component is contained in the form of derivative. The sustained-release aromatic of the present invention is useful for applications on the skin, head skin or hair of human beings or animals, on clothes, or in drinks and foods, or as an indicator for detecting micro-organisms.

Sustained-release aromatic and method of detecting micro-organism by using the same

&agr;-hydroxy fatty acid derivatives and external compositions containing the same

Surfactant, and an emulsion-type cosmetic composition and a lipsome containing said surfactant

Growing community of inventors

Kanagawa, Japan

Takeshi Ikemoto