Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai

Takeshi Hara

Tomio Takeuchi

Shinichi Kondo

Masa Hamada

Masaji Sezaki

Shuichi Gomi

Haruo Yamamoto

Benanomicin A and Benanomicin B are fermentatively produced by the cultivation of a new microorganism Actinomadura spadix, designated as MH193-16F4 strain.

Process for the simultaneous production of benanomicins A and B

Two new antibiotics which are now nominated as benanomicin A and benanomicin B, respectively, are fermentatively produced by the cultivation of a new microorganism, designated as MH193-16F4 strain, of Actinomycetes. Benanomicins A and B each show antifungal activity and are useful as a therapeutic antifungal agent. A new compound, dexylosylbenanomicin B is now produced by chemical conversion of benanomicin B, and this semi-synthetic antibiotic also shows antifungal activity and is useful as a therapeutic antifungal agent.

Antibiotics, dexylosylbenanomicin B

Benanomicins A and antibiotic compositions

Growing community of inventors

Komae, Japan

Takeshi Hara