Hamamatsu-photonics K.k.

Hamamatsu Photonics Kabushiki Kaisha

St. Marianna University School of Medicine

Agency of Industrial Science and Technology

Ministry of International Trade & Industry

Takeo Ozaki

Susumu Suzuki

Sumio Yagi

Naotoshi Hakamata

Yasuaki Koyama

Tsuyoshi Kamada

Kazuyuki Ishida

Wataru Kamo

A concentration measurement apparatus includes a light input unit for inputting measurement light to a measurement target portion, a light detection unit for detecting the measurement light propagated inside the measurement target portion, and generating a detection signal according to an intensity of the measurement light, and a calculation unit for obtaining hemoglobin-related information based on the detection signal. The calculation unit performs filter processing of extracting a component derived from respiration among frequency components included in the detection signal, the hemoglobin-related information, or a numerical value appearing in a calculation process of the hemoglobin-related information for obtaining the hemoglobin-related information in a vein of the measurement target portion.

Concentration measurement device and concentration measurement method

A concentration measurement apparatus measures a temporal relative change amount (&#x394;cHb, &#x394;OHb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (&#x394;cHb, &#x394;OHb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (&#x394;cHb, &#x394;OHb).

Concentration-measurement device and concentration-measurement method

A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.

Perform measurement of blood flow using physiological salt solution, which is harmless to living objects, as a tracer. The head portion (4) of a subject is alternately irradiated with laser light 1, and laser light 2. The light exiting from the head portion (4) is detected and converted to an electric signal. By performing a first calculation on this electric signal, a CPU (1) outputs a signal representing the change in concentration of hemoglobin in the head (4). Further, a second calculation process is performed on the electric signal which represents changes in concentration of hemoglobin generated by injection of the physiological salt solution. At least one of the blood flow or the absolute concentration of oxyhemoglobin and deoxyhemoglobin is displayed. Because a material safe to living objects is used as the tracer, measurement of the blood flow can be safely and repeatedly performed.

Diagnostic device for measuring information on blood in a living object

An examination apparatus for measuring the oxygenation in body organs by the near infrared light transmission spectrophotometry. The invention relates to an improvement of an illumination-side fixture and a detection-side fixture. In order to hold optical fibers for introducing infrared light in their natural conditions, the fixtures are equipped with respective prisms for changing light paths by prescribed angles. Also, the fixtures are equipped with respective light-emitting diodes for indicating if the examination apparatus is in its operating condition.

Examination apparatus for measuring oxygenation in body organs

A device for analyzing fluorescent light signals consists of memory means for storing as a reference spectrum a spectrum obtained under predetermined conditions, and extraction means for extracting a predetermined component spectrum based on the results of a conversion of the reference spectrum using a specific wavelength of a measured spectrum obtained during actual measurement and a specific wavelength of the reference spectrum. The arrangement of the invention allows the spectrum of a specific component to be extracted accurately from measured spectra.

Device for analyzing fluorescent light signals

An examination apparatus which measures the oxygenation in objects with near infrared light transmission spectrophotometry and that automatically adjusts a transmission light quantity to a magnitude suitable for detection by a photomultiplier tube. The examination apparatus comprises a ring-like ND filter whose transmission factor varies along its circumference, a filter driver for automatically setting a transmission factor of a filter, and a light source control device for automatically controlling output powers of light sources.

An examination apparatus measures the oxygenation in body organs by the near infrared light transmission spectrophotometry. To inspect the examination apparatus itself before the oxygenation measurement, an illumination-side fixture and a detection-side fixture have such structures that these fixtures can be assembled together in such a manner that near infrared light is directly made incident on the detection-side fixture from the illumination-side fixture. In the midst of the measurement, the examination apparatus is regularly inspected and a photomultiplier tube can be separately inspected by employing a separate light source for inspection.

Oximeter with system for testing transmission path

An examination apparatus measures the oxygenation of body organs by using the near infrared transmission spectrophotometry. To assure the measurement reliability and the object person's safety, the examination apparatus monitors the variation of the fitting position of an illumination-side fixture by detecting the reflection light quantity from the measuring object.

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Hamamatsu, Japan

Takeo Ozaki