Meiji Seika Kaisha, Ltd.

Magik Eye Inc.

Studio Gen Inc.

Takeo Miyazawa

Eiichi Akita

Hamao Umezawa

Yukio Horiuchi

Sumio Umezawa

Shunzo Fukatsu

Taro Niida

Akiteru Kimura

Takahiro Ishii

Yujiro Yamada

Toshio Yoneta

Osamu Tsuchiya

Yuzo Kazuno

Tomaso Poggio

A distance sensor includes an image capturing device positioned to capture an image of a field of view and a first plurality of projection points arranged around a first lens of the image capturing device, wherein each projection point of the first plurality of projection points is configured to emit a plurality of projection beams in different directions within the field of view. Each projection beam of each plurality of projection beams projects a visible pattern of shapes into a space surrounding the distance sensor.

Distance sensor with directional projection beams

An image information compressing method for densely compressing image information, in particular, dynamic image information, a compressed image information recording medium for recording compressed image information, and a compressed image information reproducing apparatus capable of reproducing compressed image information at high speed in a short time are provided. Each image frame constituting a dynamic image information is divided into key frames and movement compensation frames. The key frame is divided into blocks so that an image pattern of each block is vector-quantized by using a algorithm of the Kohonen's self-organizing featured mapping. The movement compensation frame is processed such that a movement vector for each block is determined and a movement vector pattern constituting a large block is vector-quantized by using the algorithm of the Kohonen's self-organizing featured mapping. The compressed image information recording medium includes an index recording region for recording the representative vector number of each block and large blocks and a representative vector recording region for recording information corresponding to a code book. The compressed image information reproducing apparatus includes a data reading unit, a key frame restoring unit and a movement compensation frame restoring unit.

Image information compressing method, compressed image information

A new polymeric compound, MF-300, is provided, which possesses a specific protective activity against bacterial infections caused particularly by Pseudomonas aeruginosa. The compound is derived from the reaction of ribostamycin with crotonoyl chloride followed by concentration of the reaction product and by subsequent recovery therefrom of a fraction having a range of molecular weights of 10,000.about.100,000 when measured by ultrafiltration method.

Polymeric compound, MF-300, with protective activity against bacterial

A new 1-N-(.omega.-aminoalkanesulfonyl) derivative of an aminoglycosidic antibiotic such as ribostamycin, 3'-deoxy- or 3',4'-dideoxy-ribostamycin, kanamycin A or B, and 3'-deoxy- or 3',4'-dideoxy-kanamycin B exhibits a broader, antibacterial spectrum than the parent aminoglycosidic antibiotic and is useful in the therapeutic treatment of infections caused by gram-positive and gram-negative bacteria including drug-resistant strains thereof. The aforesaid derivative may be made by reaction between the parent antibiotic and an amino-protected .omega.-aminoalkanesulfonic acid halide and removal of the amino-protecting group from the condensation product.

1-N-(.omega.-aminoalkanesulfonyl) derivative of aminoglycosidic

A process for preparing a novel antibiotic, 5'-amino-3',5'-dideoxy-ribostamycin, which comprises subjecting a ribostamycin derivative represented by the formula: ##STR1## to selective sulfonylation to form a 3',5'-O-disulfonyl derivative, SUBJECTING THE THUS PRODUCED DERIVATIVE TO AZIDE-FORMING REACTION WITH SODIUM AZIDE,

Pharmaceutical composition containing

3',4'-.alpha.-Epoxyneamine and its related aminoglycosidic antibiotic derivatives containing 3',4'-.alpha.-epoxyneamine moiety in the molecule thereof are now provided, which may be in the form of their amino-protected and partially hydroxyl-protected product and which are useful as intermediates for use in the synthetic production of therapeutically valuable 3'-deoxy derivatives of aminoglycosidic antibiotics.

3'-Epi-4'deoxykanamycin B

3'-Deoxy derivatives of neamine, 6'-N-alkylneamine, kanamycin B, 6'-N-alkylkanamycin B, ribostamycin, 6'-N-alkylribostamycin and paromamine may be produced by a new process comprising reducing the 3',4'-.alpha.-anhydro derivative (namely, the 3',4'-epoxide derivative) of the aminoglycosidic antibiotics with hydrogen in an alkaline lower alkanol medium containing an alkali metal hydroxide or alkoxide dissolved therein and in the presence of a reducing catalyst such as Raney nickel. The 3',4'-.alpha.-anhydro derivative may be prepared by treating the 3'-sulfonylated derivative of the amino-protected and hydroxyl-protected neamine, 6'-N-alkylneamine, kanamycin B, 6'-N-alkylkanamycin B, ribostamycin, 6'-N-alkylribostamycin or paromamine with an alkali metal hydroxide or alkoxide in a lower alkanol to effect epoxidation between the 4'-hydroxyl group and the carbon atom substituted by the 3'-sulfonic ester group.

Growing community of inventors

Tokyo, Japan

Takeo Miyazawa