Ss Pharmaceutical Co., Ltd.

Ssp Co. Ltd

Other

Bausch-lomb Incorporated

Takemitsu Asaoka

Minoru Tokizawa

Masaru Matsumoto

Hideaki Matsuda

Sunao Takeda

Kazunori Maebashi

Susumu Sato

Hiromichi Eto

Kazuya Ishida

Yasushi Kaneko

Akihiro Shibata

Tadayuki Kuraishi

Tatsuhiko Katori

Naokata Taido

Ryuichi Kawahara

Katsumi Imamori

Fujiko Konno

Lyle M Bowman

Santosh K Chandrasekaran

Masami Takahashi

Yoshihiko Kanamaru

Samir Roy

Akira Iwasa

Yutaka Murata

Hiroshi Hasegawa

Toshiaki Nakashima

Koichi Yokoi

Terumitsu Kaihoh

Tadashi Narita

Kenichi Kukita

Tetsuo Kaneko

Takashi Narui

Junji Oono

Seiji Ishizeki

Masaki Ogawa

Tasdayuki Kuraishi

Tatsuhiko Kateri

Santosh Kumar Chandrasekaran

The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid compounds. The invention also relates to quinolone carboxylic acid compositions and methods of preparing the same.

Quinolone carboxylic acid compositions and related methods of treatment

Azole derivatives or salts thereof

Described is a triazole derivative represented by the formula (1):

Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient

Triazole derivative or slat thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient

Described is a triazole derivative represented by the formula (1): ##STR1## wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.

Triazole derivative or salt thereof, preparation process thereof and

A compound having formula (2): ##STR1## wherein R represents hydrogen, a straight or branched C.sub.1-10 alkyl group, a C.sub.7-11 aralkyl group or a C.sub.2-10 carboacyl group and m stands for 1 to 5.

Triazole derivative or salt thereof

Described is a triazole derivative represented by the formula (1): wherein R.sup.1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a halogenoalkyl and n stands for an integer of 0 to 2, or salt thereof; a preparation process of said compound and a pharmaceutical comprising said compound as an effective ingredient. The compound as described above has high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.

Triazole derivative or salt thereof preparation process thereof, and

Described is a triazole derivative represented by the formula (1): ##STR1## wherein R.sup.1 represents a lower alkyl group or an aralkyl group, R.sup.2 represents a hydrogen atom, a lower alkyl group, an aralkyl group or an acyl group, X.sup.1 and X.sup.2 are the same or different and each independently represents a hydrogen atom, a halogen atom or a trifluoromethyl group, n stands for an integer of 0 to 2 and m stands for an integer of 1 to 5, or salt thereof; and also a pharmaceutical comprising the derivative or salt thereof as an effective ingredient. The compound as described above has a high antimycotic activity and is useful for the prevention and treatment of mammalian mycotic infections.

Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. ##STR1## wherein n stands for 0, 1 or 2, X.sup.1 represents H or F and Y.sup.1 and Y.sup.2 each independently represents H, halogen or CF.sub.3.

Triazole derivative, preparation process thereof and pharmaceutical

Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. wherein n stands for 0, 1 or 2, X.sup.1 represents H or F and Y.sup.1 and Y.sup.2 each independently represents H, halogen or CF.sub.3.

Triazole derivative and pharmaceutical comprising the same as an

Described is a triazole derivative represented by the formula (1): wherein R represents a hydrogen atom, an alkyl group, an aralkyl group or an acyl group, n stands for 0 to 2 and m stands for 1 to 5 or salt thereof, and a pharmaceutical containing the derivative or salt as an effective ingredient.

Growing community of inventors

Narita, Japan

Takemitsu Asaoka