Seikagaku Kogyo Kabushiki Kaisha

Seikagaku Kogyo Kabushiki Kaisha (seikagaku Corporation)

Sanyo Chemical Industries, Ltd.

Takehisa Matsuda

Katsukiyo Sakurai

Minoo J Moghaddam

Hiroshi Nakao

Hiroyuki Kito

Nobuyuki Nakajima

Tetsuji Sanyo Chemical Industries Ltd Yoshimura

Tetsuya Sanyo Chemical Industries Ltd Yamada

Material to be worn on the eyeball

Photocurable glycosaminoglycan (GAG) derivatives and crosslinked glycosaminoglycans, which are highly safe and biocompatible, a method of preparing such photocurable GAG derivatives readily moldable by casting using a solvent when desired, by which method unreacted substances causative of adverse effects can be readily eliminated, and a method of producing the crosslinked GAGs and medical materials based on the photocurable GAG derivatives or crosslinked GAGs are provided. The photocurable GAG derivatives comprise a glycosaminoglycan and a photoreactive compound bound thereto and can be produced, for example, by subjecting hydroxyl or carboxyl groups of the glycosaminoglycan to esterification reaction or amidation reaction, respectively, with the photoreactive compound. The crosslinked GAGs are derived from the photocurable GAG derivatives by intermolecular crosslinking of the photoreactive compound bound thereto.

Photcurable glycosaminoglycan derivatives, crosslinked

This invention provides a more functionalized artificial blood vessel which can be organized by independently designing its inner and outer surfaces and endowing them with respectively different biocompatibilities, as well as a process for producing the same. The artificial blood vessel comprises a tubular support having a layer of photogelled cinnamic acid-bound chondroitin sulfate coated on the inner surface thereof and a layer of photogelled coumarin-bound gelatin coated on the outer surface thereof. The process for producing the above artificial blood vessel comprises coating a layer of coumarin-bound gelatin on the outer surface of a tubular support and a layer of cinnamic acid-bound chondroitin sulfate on the inner surface of the support and irradiating each of the layers with light.

Artificial blood vessel and process for producing the same

Photocurable glycosaminoglycan derivatives, crosslinked

Growing community of inventors

Osaka, Japan

Takehisa Matsuda