Mitsubishi Kasei Corporation

Mitsubishi Chemical Industries Limited

Takayuki Tashiro

Tsuyoshi Ito

Hiroshi Kusano

Eiji Miyata

Takaharu Itagaki

Hiroaki Takayanagi

A process for producing an aminophosphoric acid-type chelate resin, which comprises aminating halomethyl groups of a polymer having the halomethyl groups on aromatic nuclei, followed by phosphomethylation, wherein the amination reaction is conducted by means of an amine mixture comprising a monoamine and a polyamine, wherein the proportion of the monoamine to the total amount of both amines is from 20 to 70% by mole.

Process for producing an aminophosphoric acid-type chelate resin

A composite separating agent which comprises a hydrophilic polymer separating agent showing a degree of swelling in water of 10 to 100 ml/g-dry and having a giant network structure incorporated within pores of an organic polymer substrate showing a degree of swelling in water of 20 ml/g-dry or below and a degree of crosslinking of 4% to 100% by mol and having a porous structure as well as a process for producing the same are disclosed. When packed within a column, this composite separating agent having a high mechanical strength is hardly compacted and exhibits an excellent separation performance. Thus it is highly useful in chromatographic separation of biopolymers including proteins.

Composite separating agent

Porous cross-linked polyvinyl alcohol particles which is used for a chromatographic medium is prepared by:

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Machida, Japan

Takayuki Tashiro