Nippon Shinyaku Company, Ltd.

Takayuki Ozaki

Shoichi Chokai

Hiroshi Enomoto

Hiromu Murai

Katsuya Ohata

Katsuhide Saito

Yoshiaki Yoshikuni

Mitsuhiro Maehara

Mitsuhiro Machara

Yoji Ezure

Fusao Ueda

Makoto Sugiyama

Nobutoshi Ojima

Yukio Fujita

Jun Segawa

Haruo Tanaka

Hirotsugu Yoshida

Ken-ichi Nakamura

Triazine derivative and medicine

Compounds of formula I are useful in the prophylaxis or treatment of hyperglycemic symptoms ##STR1## wherein R is alkyl substituted by one or more hydroxy.

Glucosylmoranoline derivatives and use thereof for inhibiting increase

Compounds of formula (I) ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 is hydrogen, halogen or alkyl and R.sup.2 is hydrogen or alkyl are useful to reduce serum lipids in animals, including humans.

Benzoic acid derivatives

Abietamide derivatives of the formula I ##STR1## wherein X is NZ wherein Z is hydrogen, alkyl, unsubstituted or substituted phenyl or X is a sulphur atom; when X is NZ, V is nitrogen, W is , and R is hydrogen or alkyl and when X is a sulphur atom, V is  , W is nitrogen, and R is hydrogen, alkyl, phenyl or --CH.sub.2 COOR'; wherein R' is hydrogen or alkyl and  is a single or double bond, are useful for treating hyperlipemia and particularly for the prevention and therapy of arteriosclerosis.

Abietamide derivatives

A series of new 4,6-disubstituted 2-morpholinone derivatives were prepared either by a reaction of corresponding epoxide derivatives with phenylglycine derivatives or by the reaction of isopropanol derivatives with carboxylic acid derivatives. The new morpholinone derivatives are useful for the prevention or the treatment of arteriosclerosis.

Morpholinone derivatives and method of use

New carboxylic acid derivatives are proposed for use as agents in the treatment or prevention of arteriosclerosis. 1-(p-chlorophenoxy)-3-(N-phenyl-N-carbomethoxymethylamino)-2-propanol is a typical compound.

Substituted N-(carboxymethyl)-3-aminopropan-2-ol derivatives

New carboxylic acid derivatives are proposed for use as agents in the treatment of prevention of arteriosclerosis. 1-(p-chlorophenoxy)-3-(N-phenyl-N-carbomethoxymethylamino)-2-propanol is a typical compound.

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Moriyama, Japan

Takayuki Ozaki