Sekisui Medical Co., Ltd.

Arkray, Inc.

Takayuki Oka

Takuya Yotani

Hideki Muraki

Hiroaki Taira

Masato Nishikawa

Takeshi Takagi

Akira Sezaki

Toshikatsu Sakai

Tatsuo Kamata

Makoto Takahara

Chiaki Miyamoto

Takeshi Asami

A gradient liquid feed device allows reduction in size of a high performance liquid chromatography type sample analyzer. The gradient liquid feed device includes a plurality of carrier liquid reservoir tanks configured to store carrier liquids of mutually different compositions, a plurality of single plunger pumps capable of drawing and discharging the carrier liquid from the plurality of carrier liquid reservoir tanks, a mixer configured to mix the carrier liquids discharged from the plurality of liquid feed pumps and feed the mixed carrier liquid, and a pulse damper in communication with the mixer and configured to absorb pulsation that may occur during liquid feeding. The single plunger pumps have a function for variably setting a length of stroke for drawing and discharging the carrier liquid and a function for variably setting a ratio between the carrier liquid drawing time and the carrier liquid discharge time.

Gradient liquid feed device for sample analyzer

A switching valve includes: (A) a rotor including: (1) a center pipe connection port, (2) a first in-valve flow path in communication with the center pipe connection port, and (3) an arc-like second in-valve flow path; (B) a stator including: (4) a first pipe connection port group which is brought into communication independently with the center pipe connection port via the first in-valve flow path when the rotor is turned, and (5) a second pipe connection port group which is brought into mutual communication via the second in-valve flow path when the rotor is turned; and (C) an arrangement of the rotor and the stator satisfying the following relationship: the state of communication or non-communication among the second pipe connection port group via the second in-valve flow path is switched in accordance with the state of communication between the first pipe connection port group and the center pipe connection port.

Switching valve for flow type analysis apparatus

Provided is a sample injection device for flow-type analysis including a cylindrical needle () which penetrates through an upper wall and a lower wall of a sample injection portion () of a carrier-liquid channel through ring-like sealing members (). The needle () includes an inner hole () which is closed on a side of a lower end of the needle () and open on an outer peripheral surface as a horizontal hole (). The needle moving unit () induces the needle () to move downward so that the horizontal hole () faces an inside of a sample vessel () to draw the sample to the inside of the needle (). Then the moving unit () induces the needle () to move upward so that the horizontal hole () faces an inside of the sample injection portion () to inject the sample in the inside of the needle (). At an intermediate position, washing liquid is discharged from the horizontal hole () of the needle (), and the washing liquid is recovered via a discharge path ().

Sample injection device for flow-type analysis device, flow-type analysis device, and measurement method for hemoglobin component

A cylindrical column body () holds a filler. A pair of end caps () covers both ends of the column body () and has a flow hole for a carrier liquid () arranged in the center thereof. An end surface on the side of a large diameter portion () of a pair of columnar joint members () contacts an end surface of the pair of end caps () and also has a communication hole () arranged in the center thereof. A sealing member () is arranged on a contact surface between the end cap () and the joint member (). A bottomed cylindrical case () accommodates the pair of end caps () and a large diameter portion of the pair of joint members () in an engaged state. A cover member () is detachably installed on a side of an opening of the case ().

Column device for liquid chromatography and liquid chromatography apparatus

When injecting a sample into carrier-liquid channels (A andB), injection shock is prevented. Septaandconstitute the upper wall and the lower wall of a sample injection part () of the carrier-liquid channels (A andB). A needle () can vertically penetrate the septum () on the upper wall side and also penetrate the septum () on the lower wall side. A needle moving unit () induces the needle () to penetrate the septum () on the lower wall side and induces the tip of the needle to face the inside of a sample vessel (). A measurement pump () is operated for drawing and as a result a sample is drawn into the needle (). Next, the needle () is extracted from the septum () on the lower wall side, the tip of the needle is induced to face the inside of the sample injection part (), the measurement pump () is caused to discharge and as a result the sample within the needle () is injected.

Sample injection device for biochemical analysis, flow-type biochemical analysis device, and measurement method for hemoglobin component

A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.

Liquid chromatography apparatus and liquid chromatography

An object of the present invention is to provide a method for analyzing hemoglobins which can accurately separate hemoglobins in a short time by liquid chromatography. The method for analyzing hemoglobins by liquid chromatography includes pretreating a sample with an oxidant and a binder for trivalent heme iron.

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Tokyo, Japan

Takayuki Oka