Nissan Chemical Industries Limited

Taisho Pharmaceutical Co., Ltd.

Takayuki Nagatsuka

Takaaki Ishii

Toshio Nakamura

Toshihito Kumagai

Taketoshi Okubo

Yoshinori Sekiguchi

Takanori Shimizu

Toru Tsukagoshi

Kumi Abe

Xiang-Min Sun

Tomoko Ishizaka

Yuri Amada

Tomoyuki Matsuda

Shigetada Sasako

Norio Hashimoto

Disclosed is an aminopyrrolidine compound represented by the formula [I] or a pharmaceutically acceptable salt thereof. The compound or the salt is useful as a prophylactic/therapeutic agent for mode disorder such as depression, anxiety disorder, anorexia, cachexia, pain and drug dependence, whose action relies on the MCreceptor antagonistic effect.

Aminopyrrolidine compound

This invention relates to benzopyran compounds of formula (I) wherein X is NR, Y is a bond, SO or SO, Z is Calkyl group or phenyl group, W is hydrogen atom, hydroxy group, Calkoxy group, a halogen atom, Calkyl group or Calkylsulfonylamino group, Rand Rare independently of each other Calkyl group, Ris hydrogen atom, hydroxy group or methoxy group, m is an integer of 0 to 4, n is an integer of 0 to 4, V is a single bond, CRR, NR, O, S, SO or SO, Ris hydrogen atom or Calkyl group, Ris hydrogen atom, Calkyl group, Ccycloalkyl group, Ccycloalkenyl group, Caryl group or Cheteroaryl group. These compounds are useful as an anti-arrhythmic agent.

Benzopyran compound

Growing community of inventors

Funabashi, Japan

Takayuki Nagatsuka