Mitsubishi Tanabe Pharma Corporation

Tanabe Seiyaku Company, Limited

Drug Delivery System Institute, Ltd.

Mitsubishi Electric Corporation

Kyb Corporation

Shanghai Pharmaceuticals Holding Co., Ltd.

Fuji Jukogyo Kabushiki Kaisha

Top Co., Ltd.

Takayuki Kawaguchi

Sumihiro Nomura

Kenji Tsujihara

Toru Iijima

Hidenori Akatsuka

Satoshi Okuno

Toshiro Yano

Toshiyuki Kume

Ila Sircar

Mikiko Tsukimoto

Jun Murakami

Tatsuya Watanabe

Kazuhiro Inoue

Jingkang Shen

Guangxin Xia

Katsutoshi Aono

Hiroshi Sugama

Jianshu Xie

Yoichi Takahashi

Nobumasa Awai

Teruomi Ito

Takashi Mitsui

Tomoki Watanabe

Yasuo Yamamoto

Masamichi Morimoto

Yasuhiko Sasaki

Yoshiteru Kurokawa

Takeo Iwakuma

Miki Hirai

Toyoharu Yamashita

Kuniya Sonehara

Tamotu Shimazaki

Masahiro Ikeda

Masatoshi Kakushima

Marshall Morningstar

Sayaka Ueno

Tarou Matsumae

Hiroyuki Miyoshi

Yasunori Tsuboi

Ryuichi Kaneko

Tomomi Hayase

Shun Matsuda

Shunsuke Okada

Hiroshi Ishihara

Hidefumi Kaji

Tomihisa Yamakawa

Yumi Najima

Kazutaka Nakamoto

Atsushi Sasaki

Toru Iljima

Akihiro Kawabata

A transformer includes: a base that is a plate-like member and has a first surface and a second surface, a core attached to the first surface of the base, coils wound around the core, coil terminals attached to the second surface of the base, and a cooling unit that is thermally connected to the core and is to release heat transferred from the core. The coil terminals are disposed on the second surface of the base opposite to the first surface of the base to which the core is attached. The cooling unit is disposed on a side of the core opposite to the base.

Transformer and power conversion device

An object of the present invention is to hold a holding member appropriately in a casing. A rotary electric machine includes a rotor having a drive shaft, a stator provided on an outer periphery of the rotor, a bearing Bthat rotatably supports the drive shaft, a holding member that contains an aluminum alloy member and holds the bearing, and a casing that houses the rotor, the stator, the bearing, and the holding member. The casing is made of a member that does not grow permanently or an aluminum alloy member that is permanently grown when the holding member is fixed to the casing. The holding member is in a state before permanent growth before being fixed in the casing, and the holding member grows permanently to be fixed more firmly to the casing.

Rotary electric machine and manufacturing method of rotary electric machine

Locking members disposed on a casing of an underfloor device for railway vehicles engage hanging tools disposed on the vehicle, whereby the underfloor device for railway vehicles is attached to the vehicle. The locking member is a hollow locking member that includes a locking part to contact and engage a vertically upper face of part of the hanging tool, a mount part attached to the casing, and a connection part connecting the locking part and the mount part. The locking part is disposed at a position spaced apart from the casing horizontally and vertically upward. The locking part contacts and engages the vertically upper face of part of the hanging tool inserted into a space surrounded by the locking part, the mount part, and the connection part.

Underfloor device of railway vehicle

A rotor manufacturing method for manufacturing a rotor including a rotor core, the rotor core having a permanent magnet mounted thereon throughout a circumferential direction, includes covering an outer circumference of the rotor core with a tubular rotor cover; and forming an angular portion conforming to an outer shape of the permanent magnet by pressing an open end of the rotor cover radially inward with use of a pressing member, the open end of the rotor cover axially projecting from an end of the rotor core before being pressed.

Rotor and rotor manufacturing method

The present invention provides a nitrogen-containing saturated heterocyclic compound of the formula [I]: wherein Ris a cycloalkyl group and the like, Ris an optionally substituted aryl and the like, R is a lower alkyl and the like, T is a carbonyl group, Z is &#x2014;O&#x2014; and the like, and Rto Rare the same or different and a hydrogen atom and the like; or a pharmaceutically acceptable salt, that is useful as a renin inhibitor.

Nitrogen-containing saturated heterocyclic compound

A rotorincludes a rotor corefixed to a rotation axis in such a manner that the rotor coreis rotatable integrally with the rotation axis, the rotor corebeing configured to have a plurality of magnetsmounted thereon throughout a circumferential direction; a first rotor coverthat includes a first tubular portion, the first tubular portionhaving a tubular shape configured to cover an outer circumference of one axial side of the rotor core; and a second rotor coverthat includes a second tubular portion, the second tubular portionhaving a tubular shape configured to cover an outer circumference of the other axial side of the rotor core. An outer diameter of the first tubular portionis configured to be larger than an inner diameter of the second tubular portion, and the first rotor coverand the second rotor coverare configured to be fixed to each other by press fitting to have the first tubular portionarranged at an inner circumferential side of the second tubular portion

Rotor, method of manufacturing the rotor, and rotary electric machine having the rotor

Semiconductor elements work for power conversion and generate heat. A plurality of heat-radiating fins are juxtaposed at intervals to form a passage in a first axis direction, receive the heat from the semiconductor elements, and expel the heat into the air flowing through the passage. A first protective fin has an end face having an equal length in the juxtaposition direction to and mutually facing the end face on the first axis positive side of at least some of the heat-radiating fins, and extends in the first axis positive direction from that end face. A second protective fin has an end face having an equal length in the juxtaposition direction to and mutually facing the end face on the first axis negative side of at least some of the heat-radiating fins, and extends in the first axis negative direction from that end face.

Vehicular power conversion device

The present invention provides a nitrogen-containing saturated heterocyclic compound of the formula [I]: wherein Ris a cycloalkyl group and the like, Ris an optionally substituted aryl and the like, R is a lower alkyl and the like, T is a carbonyl group, Z is &#x2014;O&#x2014; and the like, and Rto Rare the same or different and a hydrogen atom and the like;or a pharmaceutically acceptable salt, that is useful as a renin inhibitor.

The present invention provides a morpholine derivative of the formula [I]; wherein Ris a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, a cycloalkyl group or an alkyl group; Ris a substituted alkyl group, an optionally substituted aryl group, an optionally substituted heterocyclo group, an optionally substituted alkylcarbonyl group, an optionally substituted arylcarbonyl group, an optionally substituted heterocyclo-substituted carbonyl group or a cycloalkylcarbonyl group; T is a methylene group or a carbonyl group; R, R, Rand Rare the same or different and a hydrogen atom, an optionally substituted carbamoyl group or an optionally substituted alkyl group;or pharmaceutically acceptable salts thereof. These compounds are useful as a renin inhibitor.

Morpholine derivative

The present invention relates to a phenylalanine derivative of Formula (I) wherein Xis a halogen atom, Xis a halogen atom, Q is a CHR&#x2014; is a carboxyl group which may be esterified; or a pharmaceutically acceptable salt thereof.

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Fused bicyclic compound having an affinity to mineral corticoid receptor (MR), of formula [I]: wherein ring A is benzene having a substituent R, fused to an adjacent 6-membered heterocyclic ring and further optionally having a substituent(s) other than R, Ris alkylsulfonylamino, etc., Rand Rare (a) the same of different and are hydrogen, alkyl, or optionally substituted aryl, or (b) combined with each other to form an oxo group or (c) combined with each other at its terminal together with the adjacent carbon atom to form cycloalkyl, X is &#x2550;N&#x2014;, &#x2550;C(R)&#x2014; or &#x2014;CH(R)&#x2014;, Ris (a) hydrogen, (b) cyano, (c) halogen, (d) alkyl, (e) alkenyl, (f) cycloalkyl, (g) alkanoyl, (h) carbamoyl, or (i) cycloalkenyl, Ar is an optionally substituted aromatic cyclic group and a dotted line means presence or absence of a double bond, or a pharmaceutically acceptable salt thereof, useful e.g. as an antihypertensive agent.

Fused bicyclic compound

The present invention provides a novel fused bicyclic compound having an affinity to a receptor of mineral corticoid (MR), shown by the formula [I]: wherein the ring A is a benzene ring having a substituent R, fused to an adjacent 6-membered heterocyclic ring and further optionally having a substituent(s) other than R, Ris an alkylsulfonylamino group etc.,

The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than Retc, Ris a group of the formula: RSONH&#x2014; etc, Ris an alkyl group etc, Rand Rare each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: &#x2014;C(&#x2550;O)&#x2014; etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.

Benzoxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents

Growing community of inventors

Tokyo, Japan

Takayuki Kawaguchi