The Brigham and Women's Hospital, Inc.

Biolegend, Inc.

Takatoku Oida

Howard L Weiner

Galina Gabriely

Andre Pires Da Cunha

Anagha Ashok Divekar

Nicole Vivienne Acuff

Juan E Moyron-Quiroz

Compositions and methods for making and using anti-TLR9 agents, for example, monoclonal antibodies, TLR9-binding antibody fragments, and derivatives are described, as are kits, nucleic acids encoding such molecules, diagnostic reagents and kits that include anti-TLR9 agents, and methods of making and using the same.

Anti-TLR9 agents and compositions and methods for making and using the same

Compositions and methods for making and using anti-TSPAN33 agents, for example, monoclonal antibodies, TSPAN33-binding antibody fragments, and derivatives, are described.

Anti-tetraspanin 33 agents and compositions and methods for making and using the same

Described herein are compositions and methods relating to LAP-binding agents, including, for example, anti-LAP antibodies, and to their use in methods of treatment of cancer. LAP-binding agents affected both systemic and intra-tumor immunity and were shown effective to treat a broad spectrum of cancer types.

Treatment of cancer with anti-LAP monoclonal antibodies

Treatment of cancer with anti-lap monoclonal antibodies

Growing community of inventors

Osaka, Japan

Takatoku Oida