The University of Tokyo

Riken Corporation

Kisco

Daisan Kasei Co., Ltd

Takatoki Yamamoto

Teruo Fujii

Yasuyuki Sakai

Takashi Inoue

Isao Endo

Masaki Nishikawa

Jong Wook Hong

Shin Ohya

Hitomi Sakai

Hirosuke Naruto

The invention is directed to methods for the propagation or cultivation of cells including preparing a cell culture substrate, wherein the cell culture substrate includes a substrate and a layer formed by surface modification. The layer includes a polymer containing an amino group. The polymer is produced by reacting a polymer represented by formula (II): with a polymer having at least one amino group, &#x2014;NH, capable of forming a Schiff base in a monomer of formula (II), thereby forming a polymer layer constituting the layer formed by surface modification. 'n' in Formula (II) is 0 or a positive integer, and m is a positive integer. n and m represent the degree of polymerization. Formula (II) is formed by chemical vapor deposition of formyl[2.2]paracyclophane. The methods further include providing cells in a medium; inoculating the cells onto the cell culture substrate; and culturing the cells, wherein the cells adhere to the cell culture substrate.

Cell culture substrate and its production method

In order to be capable of a chemical reaction, analysis or the like wherein a small amount of samples is used, a reactor comprises a flat plate-like first substrate the inside of which is provided with a heating means; and a flat plate-like second substrate, which is placed on the top of the above-described first substrate, and on a surface thereof to be placed on the top of the above-described first substrate a flow channel having a predetermined contour has been defined.

Reactor and process for production thereof

Growing community of inventors

Bunkyo-ku, Japan

Takatoki Yamamoto