Daikin Industries, Ltd.

National Institute of Advanced Industrial Science and Technology

The Jikei University School of Medicine

The University of Tokyo

Advanced Bio-spectroscopy Co., Ltd

Takashi Ushida

Junichiro Arai

Hideo Katayama

Sadayori Hoshina

Chiaki Okumura

Yoshihisa Amano

Katsuhiko Machida

Seizi Nishizawa

Katsuko Furukawa

An object is to provide a technique that can evaluate biological tissues such as cartilage tissue and regenerated tissues such as regenerated cartilage. A method for observing a dynamic physical property of a biological tissue according to the present invention is that a biological tissue is irradiated with a pulsed light having a wavelength of a far-infrared wavelength region modulated into circular polarized lights by applying bias voltages to a radiation means () having an antenna electrode films of orthogonal ()-axis structure with phases shifted using high-voltage high-speed modulation means (), and dynamic physical property of the biological tissue is observed on the basis of a spectrum obtained by vibration optical activity spectroscopy.

Method for observing dynamic physical property of biological tissue and device for observing dynamic physical property of biological tissue

Disclosed herein is a method for determining the drug sensitivity of a microbe which comprises pouring a microbial suspension into each of the compartments or wells at a position which is in the vicinity of an electrode for measuring dissolved oxygen concentration, measuring current from each electrode at a second time interval for a third time period, each time is obtained based upon each of the measured currents at which the maximum current is obtained, obtaining each current value within a fourth time period which starts from the time at which the maximum current is obtained, detecting drug sensitivity based upon the variation condition of each current value during the fourth time period. The method allows rapid drug susceptibility measurements.

Drug sensitivity measuring method

A method and apparatus wherein measurement current values output from a first oxygen sensor and a second oxygen sensor are time sequentially measured. Each moving average value is calculated from each sequential measurement current value. Each time differential value is calculated from the pair of each calculated moving average values, by least squares approximation. Then, drug susceptibility is measured based upon each calculated time differential value, so that drug the susceptibility measurement is performed quickly or accurately.

Drug susceptibility measurement method and apparatus thereof

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Ibaraki, Japan

Takashi Ushida