Osaka University

Suntory Holdings Limited

Hamamatsu University School of Medicine

National University Corporation Hamamatsu University School of Medicine

Takashi Ooshima

Yuko Fukui

Kazuo Umemura

Kazuya Hokamura

Kazuhiko Nakano

Ryota Nomura

Koichiro Wada

Michiyo Nakano

Disclosed is the construction of a system capable of quickly and easily identifying patients having a risk for worsening inflammatory digestive tract disease by identifying a causal factor for the worsening of the inflammatory digestive tract disease. Specifically disclosed is a method for detecting oral bacteria that cause worsening of inflammatory digestive tract disease and/or a screening that targets high risk for worsening of inflammatory digestive tract disease and/or determining the risk for worsening of the inflammatory digestive tract disease by PA not being detected and/or CBP being detected, inclusive of the detection of PA, which is an oral bacteria protein antigen, and/or CBP, which is collagen binding protein, in samples. Also disclosed are a detection reagent and kit used for this method.

Production of enteritis evoking causal factor by highly pathogenic oral bacteria and high sensitivity detection method therefor

Provided is a highly palatable and safe glucosyltransferase inhibitor or anti-dental caries agent. A glucosyltransferase inhibitor or anti-dental caries agent having an epigallocatechin gallate polymer or a salt thereof. Particularly, the above agent containing an epigallocatechin gallate polymer, which is a compound in which chroman rings are bonded at position 6 and/or 8 via a methylene group.

Glucosyltransferase inhibitor containing epigallocatechin gallate polymer as active ingredient

Growing community of inventors

Suita, Japan

Takashi Ooshima