Meiji Seika Pharma Co., Ltd.

Takashi Matsuhira

Takeru Yamakawa

Yuji Tabata

Keiji Tamura

Satoshi Isshiki

Yoshinari Wakiyama

Shohei Ouchi

Natsuki Ishida

Chika Kikuchi

Naoko Watanabe

Kaori Kaneda

Natsuki Kubota

A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1),

Therapeutic agent for inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases

A compound represented by the general formula (1) below or a pharmacologically acceptable salt thereof: [In the formula (1),

Compound and pharmacologically acceptable salt thereof

Provided is a compound represented by formula (1a) or a pharmacologically acceptable salt thereof, which can be used as a phosphodiesterase (PDE) inhibitor. Rto Rin the formula each independently represent an alkyl group or the like. 

PDE4 inhibitor

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Yokohama, Japan

Takashi Matsuhira