Yamasa Corporation

Toa Eiyo Ltd.

Other

Takashi Konno

Yoshikazu Kato

Kazuhiro Uemoto

Shinya Onuma

Toichi Abiru

Kazuki Endo

Miwa Misawa

Tomokazu Hosokawa

2-(6-Cyano-1-hexyn-1-yl)adenosine, 2-(6-cyano-1-hexyn-1-yl)adenosine 5'-monophosphate, or salts thereof; and drugs containing the same as an active ingredient. The compounds have excellent effects of lowering ocular tension, promoting blood flow in retina, and protecting optic nerve failure and are highly soluble in water. Owing to these characteristics, the compounds are useful as drugs such as remedies for glaucoma and ocular hypertension.

Adenosine derivatives and use thereof

Medicinal compositions for treating eye diseases which contain as the active ingredient 2-alkynyladenosine derivatives having an acetylene union at the 2-position of adenine base. Having a long-lasting and remarkable effect of lowering ocular tension, these compositions are useful as remedies for eye diseases accompanying increased ocular tension or optic nerve failures, such as glaucoma and hypertonia oculi.

Medicinal compositions for treating eye diseases

Growing community of inventors

Fukushima, Japan

Takashi Konno