Mitsubishi Tanabe Pharma Corporation

Takashi Goi

Norimitsu Hayashi

Osamu Sakurai

Hiroaki Sawamoto

Ritsuo Imashiro

Kenji Morokuma

Kunio Saruta

Hiroaki Shitama

Hidekazu Tsujishima

This is to provide a continuous arycyclic compound having a DGAT1 inhibitory activity, and useful for prophylaxis and/or treatment of obesity or hyperlipidemia caused by obesity, hypertriglyceridemia, lipid metabolism disorder, fatty liver, hypertension, arteriosclerosis, diabetes, etc., as well as to provide a DGAT1 inhibitor comprising the continuous arycyclic compound or a pharmaceutically acceptable salt thereof as an effective ingredient. Disclosed is the continuous arycyclic compound is represented by the formula: wherein the substituents in the formula are the same as defined in the specification, or a pharmaceutically acceptable salt thereof. 

Continuous arycyclic compound

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Osaka, Japan

Takashi Goi