Other

Nipro Corporation

Kawasumi Laboratories. Inc.

Taki Chemical Co., Ltd.

Takao Okada

Yukari Imamura

Noriaki Shirahama

Yoshimichi Fujiyama

Junzo Tanaka

Nobutaka Fujimoto

Shigeki Hamamoto

Morio Nakamura

Masanori Kikuchi

Masato Fujikake

Makoto Sato

Kimihiko Kondo

Kazuo Takakuda

Yoshihisa Koyama

Kunio Takaoka

Tomokazu Mukai

Naoto Saito

Yohei Hoashi

Tatsuaki Miyaji

Kimihiro Miyamoto

Takatoshi Itoh

Shigeo Tanaka

Soichi Shono

Etsuro Yokoyama

Shunji Ichikawa

Shuji Suwa

Hisae Saito

Tamaki Murayama

Noriaki Kawasumi Laboratories Inc Shirahama

Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/&#x3b5;-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater,2&#x3c;()&#x3c;[%/(%+%+%)]&#xd7;&#xd7;0.058&#x2003;&#x2003;(1)1&#x3c;()&#x3c;[%/(%+%+%)]&#xd7;&#xd7;0.58&#x2003;&#x2003;(2)1&#x3c;()&#x3c;[%/(%+%+%)]&#xd7;&#xd7;0.58&#x2003;&#x2003;(3) wherein L(LA), L(GA) and L(CL) represent average chain lengths of lactic acid units, glycolic acid units and of caprolactone units, LA%, GA% and CL% represent molar ratios of a lactic acid component, a glycolic acid component caprolactone component in the copolymer and X is a polymerization degree of the copolymer.

Artificial dura mater and process for producing the same

A bioabsorbable release-sustaining pharmaceutical formulation using a biodegradable release-sustaining base material which can prevent an effective component drug from being released too rapidly just after administration of the formulation and then allow continued release of the drug for at least one month at a defined rate, is provided. For the biodegradable release-sustaining base material, a lactic acid-glycolic acid copolymer (PLGA) with an adjusted distribution in molecular weight is used.

Bioabsorbable pharmaceutical formulation

Biological materials

The present invention offers biomaterials exhibiting excellent sustained-release property and degradation property such as that polypeptides or the like having a biological activity can be continuously released for a prescribed life span in vivo. The said biomaterials consist of a copolymer prepared by the reaction of lactic acid and/or glycolic acid and p-dioxanone with polyethylene glycol as main components.

Drug sustained-released biomaterial

A method for producing a highly concentrated aqueous acrylic amide-based polymer dispersion which is inexpensive, good in fluidity and easy to handle is provided. The method comprises polymerizing a water-soluble monomer composition containing an acrylic amide monomer in an aqueous solution of an inorganic salt in the presence of a homopolymer of vinylpyrrolidone and/or a copolymer of vinylpyrrolidone and other monomer(s).

Aqueous polymerization of acrylamide in the presence of polyvinylpyrrolidone

An automatic locking device for an automobile door which can automatically lock a door a few seconds after the key is removed from the ignition switch and the door is closed. The device includes a key switch for detecting the insertion and removal of a key, a door switch for controlling the power source, and time-differential-type relays for operating an actuator.

Automatic locking device for automobile door

Growing community of inventors

Kakogawa, Japan

Takao Okada