Sumitomo Chemical Company, Limited

Dainippon Sumitomo Pharma Co., Ltd.

Takanori Okahashi

Kazuhiko Takahashi

Hiroharu Takeshima

Koji Fujimoto

Yasuko Yamauchi

Seigo Ito

A stabilized amrubicin hydrochloride composition which comprises 3 to 8 wt. % water and 92 to 97 wt. % amrubicin hydrochloride; and a method of storing amrubicin hydrochloride.

Stabilization of amrubicin hydrochloride

A method for producing poly(p-t-butoxystyrene), which comprises polymerizing p-t-butoxystyrene in a hydrocarbon type reaction solvent in the presence of a polymerization initiator, and, after termination of the polymerization reaction, conducting a separation of the hydrocarbon type reaction solvent layer containing poly(p-t-butoxystyrene) and the water layer in the presence of 1-50 parts by weight of a polar solvent per 100 parts by weight of the hydrocarbon type reaction solvent layer, wherein the separation efficiency, after termination of the polymerization reaction, of the hydrocarbon type reaction solvent layer containing poly(p-t-butoxystyrene) and the water or acidic water layer conspicuously improves.

Method for producing poly(p-t-butoxystyrene)

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Nishinomiya, Japan

Takanori Okahashi