Keio University

Morishita Jintan Co., Ltd.

Foundation for Biomedical Research and Innovation at Kobe

Takanori Kanai

Nobuo Sasaki

Toshiro Sato

Kentaro Miyamoto

Ryo Aoki

Nobuhiro Nakamoto

Hideo Nishimura

Hiroyuki Hayakawa

Tomoyuki Koyama

Takuhiko Adachi

An object of the present invention is to obtain a capsule for treating ulcerative colitis which, when a capsule containing indigo is orally administered, acts more effectively than conventional ones and has less side effects of hepatotoxicity by not easily disintegrating in the stomach and small intestine but only in the large intestine. The present invention relates to a capsule for treating ulcerative colitis which disintegrates locally in the large intestine, comprising a drug-containing content, a protective layer coating the content and a film formed outside the protective layer, which are arranged concentrically, wherein the content is a content in which indigo, which is a drug for treating ulcerative colitis, is dispersed or dissolved, and the film is locally disintegrated in the large intestine.

Capsule for treating ulcerative colitis

To identify a microorganism causing the development of primary sclerosing cholangitis associated with ulcerative colitis. Astrain inducing inflammation in the liver.

strain inducing inflammation in liver

Growing community of inventors

Tokyo, Japan

Takanori Kanai