Taiyo Kagaku Co., Ltd.

Minophagen Pharmaceutical Co., Ltd.

Takako Yokozawa

Lekh Raj Juneja

Tsutomu Okubo

Itsuo Nishioka

Tadao Takeuchi

Hikokichi Oura

To provide a composition for prevention, amelioration, or treatment of diabetes mellitus and/or diabetic nephropathy, which is less likely to cause any disadvantages such as side effects, and highly safe. [1] A composition for prevention, amelioration, or treatment of diabetes mellitus and/or diabetic nephropathy, containing one or more dietary fiber selected from the group consisting of a degraded galactomannan, an indigestible dextrin, a polydextrose, inulin, arabinogalactan, dietary fiber derived from corn, a water-soluble soybean polysaccharide, psyllium, and a low-molecular weight sodium alginate, and/or a polyphenol compound.

Preventive, relieving or therapeutic composition for diabetes mellitus and/or diabetic nephropathy

An antihypertensive method comprising administering to a hypertensive patient a pharmaceutical agent containing lithospermic acid B represented by the formula: ##STR1## and/or the pharmaceutically acceptable salt thereof, for example, Mg.sup.2+, K.sup.+, NH.sub.4.sup.+ and Ca.sup.2+ salts thereof, as an effective ingredient.

Antihypertensive method

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Toyama, Japan

Takako Yokozawa