Hamamatsu-photonics K.k.

Osaka Prefectural Hospital Organization

Okayama University

Takahiro Shikayama

Mitsuharu Miwa

Osamu Ishikawa

Terumasa Yamada

Kunihito Gotoh

Takayuki Sato

Takahiro Murakoshi

Kazumasa Hirawake

Aiji Ohtsuka

Akira Shinaoka

Toshiyuki Kitai

Yoshihiro Kimata

Kenjiro Hasegawa

A fluorescence observation device is a device for performing fluorescence observation of a sample piece cut out from a sample including: a tray on which the sample piece is placed; a light source unit which generates excitation light to irradiate the sample piece; a detection unit which detects fluorescence from the sample piece; and an image generation unit which generates a fluorescence image of the sample piece based on a detection signal from the detection unit and the tray includes a plurality of placement regions provided around a center region of the tray and also includes a marker portion indicating a cutting orientation of the sample piece with respect to the sample.

Fluorescence observation device

An embodiment relates to a method of evaluating a lymphatic system function including: selecting one or a plurality of lymphatic routes to be evaluated from a plurality of lymphatic routes existing in four limbs; determining an injection site of a visualization agent based on information on the selected lymphatic route and injection sites of peripheries of the four limbs corresponding to the selected lymphatic route; injecting the visualization agent from the selected injection site; and visualizing the injected visualization agent and evaluating functions of the one or plurality of lymphatic routes to be evaluated.

Method of evaluating lymphatic system function

Cover for cancer cell observation camera

The fluorescent light phantom deviceis provided with: a phantom supporthaving fluorescent light phantom containersand; and fluorescent light phantomsandwhich are constituted of a medium that reproduces at least one of light scattering and light absorption of an object to be measured and a fluorescent coloring matter contained in the medium of a predetermined concentration and are stored in the fluorescent light phantom containersand

Fluorescent light phantom device and fluorescent light imaging method

A method of detecting an accessory cancer lesion, comprising an administration step wherein indocyanine green is administered to a living body, an irradiation step wherein a target organ suspected of having cancer is surgically exposed and irradiated with excitation light of indocyanine green, an imaging step wherein a near-infrared fluorescence intensity distribution image from the excited indocyanine green in the target organ is obtained, and an identification step wherein an area having the near-infrared fluorescence in the intensity distribution image, excluding the area detected in preoperative examination or intraoperative macroscopic observation, is identified as an accessory cancer lesion.

Method for detecting cancer using ICG fluorescence method

A sentinel lymph node detecting apparatusincludes: an excitation light source unitthat illuminates an excitation lightonto a living body observation portionincluding a sentinel lymph nodenear a tumor into which a fluorescent dye that emits fluorescence is injected; an optical filterthat transmits a fluorescence image; an image pickup devicethat is integral with excitation light source unitand picks up fluorescence imagetransmitted through optical filter; an adjusting devicethat adjusts the picked-up observation image; and an image displaying devicethat displays the adjusted observation image. Adjusting deviceadjusts at least one of a luminance and a contrast of the observation image. A lymph node detecting apparatus that is simple in apparatus arrangement, is easy to handle, and enables good images to be obtained is thereby realized.

Lymph node detecting apparatus

A sentinel lymph node detecting apparatusaccording to an embodiment of the present invention includes: a light source unit, illuminating an excitation lightand an illumination lightonto a biological observation locationthat includes a sentinel lymph nodenear a tumor, into which a fluorescent dye that emits fluorescence is injected; an optical filter, transmitting a fluorescence imageand a normal image; an image pickup device, disposed integral to the light source unitand picking up the fluorescence imageand the normal imagetransmitted through the optical filter; and an image display device, displaying the observation images that have been picked up. The wavelength of the illumination lightis set to a value close to the wavelength of the fluorescence emitted from the fluorescent dye.

Growing community of inventors

Hamamatsu, Japan

Takahiro Shikayama