Nippon Soda Co., Ltd.

Osaka Prefecture University Public Corporation

Asubio Pharma Co. Ltd.

Daiichi Asubio Pharma Co., Ltd.

Takahiro Sagae

Hiroyuki Adachi

Masao Yamaguchi

Akihiro Takahashi

Takashi Kawana

Mitsuru Takase

Shigeo Mori

Toshio Aihara

Masami Koguchi

Kenichi Hayashi

Kazuyuki Tomida

Daisuke Asanuma

Osamu Miyahara

Ilhyong Ryu

Noriaki Kawahara

Hiroyuki Yazaki

Kazuyuki Tomita

Toshiyuki Watai

Masaaki Sato

This invention provides a microreactor comprising a microchamber provided with a raw material introduction port and a product discharge port; wherein solid catalysts are aligned in a line in the longitudinal direction of the microchamber to fill the microchamber.

Microreactor and liquid phase chemical reaction method using microreactor

The present invention provides a method for preparing an organic compound, which comprises a dehydration step of distilling off water from a polar organic solvent solution containing the organic compound and water to bring the concentration of water below a given level, wherein the dehydration step comprises distilling off water together with the polar organic solvent while adding a polar organic solvent to the solution, or comprises repeating several cycles of adding a polar organic solvent to the solution and then distilling off water together with the polar organic solvent. The present invention further provides the preparation of an organic compound, which enables efficient isolation of the target product in high isolated yield from a polar organic solvent solution containing the organic compound, water and, if necessary, a compound which produces, upon coming into contact with water or the like, a substance accelerating the decomposition of the organic compound.

Processes for preparation of organic compounds

There is provided a method by which various compounds (1) having a carboxyl group in the molecule have the carboxyl group converted to a (dioxolenon-4-yl)methyl ester at low cost, in a simple way and at high yield. The process for producing compounds of formula (3) according to the reaction scheme shown below comprises reacting carboxylic acids of formula (1) with 4-chloromethyldioxolenone compounds of formula (2) in a solvent in the presence of both a phase transfer catalyst and a metal iodide: [where Q represents an organic group, M represents a hydrogen atom, an alkali metal, an alkaline earth metal or a transition metal, Rand Rrepresent a hydrogen atom, an optionally substituted (Calkyl group or phenyl group)].

Process for producing (dioxolenon-4-yl)methyl ester derivative

Novel thio phenol compounds bearing heterocyclic groups as the substituent, useful as intermediates for the preparation of agricultural chemicals, particularly herbicides; intermediates for the preparation of the same; and processes for the preparation of both as represented by reaction formula (I), herein R is C -C alkyl; R is hydrogen or C -C alkyl; R is hydrogen cyano, amido, C -C alkylcarbonyl or C -C alkoxycarbonyl; R is C -C alkyl; and Q is isoxazolyl or the like.

Heterocycle-bearing thio phenol compounds, intermediates for the preparation of the same and processes for the preparation of both

The present invention is directed to a benzoic acid derivative methyl 3-formyl-4-methanesulfonyl-2-methylbenzoate. The compound is useful as a starting material for herbicide manufacture.

Heterocycle-substituted benzene derivatives and herbicides

3-(isoxazol-5-yl)-substituted benzoic acid derivative and method for

Substituted bicycloheptanedione derivative and herbicide

Growing community of inventors

Kanagawa, Japan

Takahiro Sagae